Definition of Exercise-Induced Acute Renal Failure (ALPE)

Abstract

The criteria used in a diagnosis of ALPE are listed below.

• 1. Recent intense (anaerobic) exercise such as a short-distance sprint.

• 2. Mild rhabdomyolysis (which differs from that in myoglobinuric acute renal failure patients), and serum levels of creatine phosphokinase (CPK) and myoglobin, which are normal or slightly increased (less than 7 times the reference value for serum myoglobin, and less than 9 times the reference value for CPK).

• 3. Severe loin pain several hours after exercise.

• 4. Wedge-shaped contrast enhancement on plain CT from a few hours to 72 h after the administration of a contrast medium (however, delayed CT after administration of the contrast medium is not essential to making a diagnosis).

The selection criteria for data collection are shown in Table 2.