Prevention

Abstract

Methods of preventing exercise-induced acute renal failure (ALPE) and relapse have not been established as the etiology and pathogenesis of ALPE remain to be clarified. However, the following points are important.

• 1. Sprinting in an athletics meeting should be avoided if the athlete has a cold.

• 2. Nonsteroidal anti-inflammatory drugs (NSAIDs) should not be taken before exercise.

• 3. Exercise should be avoided in conditions of high temperature or humidity, and suitable preparatory exercise must be performed.

• 4. Repeated anaerobic exercise should be avoided.

• 5. The prevention of dehydration is essential (water supplementation, no exercise after drinking alcohol).

• 6. ALPE frequently develops and recurs in patients with renal hypouricemia, and caution is needed. When a relapse is suspected, patients should immediately consult a hospital without taking analgesic agents (NSAIDs). In particular, caution is needed when the patient’s base-line serum uric acid level is 1.0 mg/dl or less.