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Multiplicity Problems in the Clinical Trial and Some Statistical Approaches

  • Chihiro Hirotsu
Conference paper

Summary

In a clinical trial there arise a variety of multiplicity problems which might cause the bias and need to be considered carefully in analyzing and interpreting the data. We first introduce those problems frequently encountered in practice and then discuss some statistical approaches to overcome the difficulty.

Keywords

Dose Level Marginal Total Multivariate Normal Model Multiplicity Problem Gency Table 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Institute of Statistical Mathematics 2002

Authors and Affiliations

  • Chihiro Hirotsu
    • 1
  1. 1.Graduate School of EngineeringUniversity of TokyoBunkyo-Ku, TokyoJapan

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