Abstract
Lactic acidosis and release of excitotoxic amino acids may contribute to secondary brain damage following head injury [1–6]. Microdialysis is one of the most promising new methods for analyzing these neurochemical alterations in the intensive care setting [7–17]. We analyzed the chemical composition of the extracellular space of the brain, which was continuously sampled using microdialysis in 15 brain-injured patients, and correlated these neurochemical data with information regarding intracranial pressure, jugular venous oxygen saturation, clinical events, and patient outcome.
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© 1995 Springer-Verlag Tokyo
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Goodman, J.C. et al. (1995). Measurement of Lactic Acid and Amino Acids in the Cerebral Cortex of Head-Injured Patients Using Microdialysis. In: Tsubokawa, T., Marmarou, A., Robertson, C., Teasdale, G. (eds) Neurochemical Monitoring in the Intensive Care Unit. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68522-7_9
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DOI: https://doi.org/10.1007/978-4-431-68522-7_9
Publisher Name: Springer, Tokyo
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