Prolonged Stimulation-Induced Afterdischarges of Hippocampal CA1 Pyramidal Cells After Ischemia In Vivo
Transient cerebral ischemia causes selective death of hippocampal CA1 pyramidal cells after a period of 3–5 days . We previously demonstrated that Schaffer collateral/CA1 responses of the rat are potentiated beginning at 6–8 h after transient cerebral ischemia in vivo . The present study examined whether the utilization of N-methyl-d-aspartate (NMDA) receptorcoupled ion channels is increased or not during the period in which postischemic potentiation (PIP) of Schaffer collateral/CAl responses is observed.
KeywordsPyramidal Cell Sham Control Population Spike Synaptic Response Repetitive Stimulation
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