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Validation of a Noninvasive Measurement of Regional Hemoglobin Oxygen Saturation

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Book cover Neurochemical Monitoring in the Intensive Care Unit

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Abstract

Near-infrared (NIR) spectroscopy may provide a continuous and noninvasive assessment of global brain hemoglobin oxygen saturation by measuring the differential absorption of infrared light [1–3]. As biological tissues are relatively transparent to infrared light at wavelengths between 400 and 1000 nm, infrared light may penetrate skin, subcutaneous tissue, bone, and dura to the brain [4–7], where it is absorbed by oxygenated hemoglobin, deoxygenated hemoglobin, and cytochrome aa3. Thus, the attenuation of infrared light of specific wavelengths by these chromophores may be used to measure brain oxygenation [1, 3, 8–11]. The hemoglobin oxygen saturation measured by the cerebral oximeter receives contributions from arterial, venous, and capillary blood vessels, with a predominantly venous contribution [11, 12], and may reflect the balance between cerebral oxygen consumption and delivery.

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, The University of Texas Medical Branch in Galveston, Suite 2A John Sealy Hospital, Galveston, Texas, 77555-0591, USA

    Valerie Pollard, Eric A. DeMelo, Donald J. Deyo, Rebecca Dalmeida & Donald S. Prough

  2. Somanetics Corp., 1653 East Maple Road, Troy, Missouri, 48083-4208, USA

    R. Widman

Authors
  1. Valerie Pollard
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  2. Eric A. DeMelo
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  3. Donald J. Deyo
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  4. Rebecca Dalmeida
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  5. R. Widman
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  6. Donald S. Prough
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Editor information

Editors and Affiliations

  1. Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan

    Takashi Tsubokawa M.D., D.Sc. (Professor and Chairman) (Professor and Chairman)

  2. Division of Neurosurgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA

    Anthony Marmarou Ph.D. (Professor) (Professor)

  3. Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA

    Claudia Robertson M.D. (Professor) (Professor)

  4. Department of Neurosurgery, Southern General Hospital, University of Glasgow, Glasgow, Scotland, UK

    Graham Teasdale M.D. (Professor and Chairman) (Professor and Chairman)

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© 1995 Springer-Verlag Tokyo

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Pollard, V., DeMelo, E.A., Deyo, D.J., Dalmeida, R., Widman, R., Prough, D.S. (1995). Validation of a Noninvasive Measurement of Regional Hemoglobin Oxygen Saturation. In: Tsubokawa, T., Marmarou, A., Robertson, C., Teasdale, G. (eds) Neurochemical Monitoring in the Intensive Care Unit. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68522-7_24

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  • DOI: https://doi.org/10.1007/978-4-431-68522-7_24

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68524-1

  • Online ISBN: 978-4-431-68522-7

  • eBook Packages: Springer Book Archive

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