The Optimal Cerebral Perfusion Pressure for Management of Patients with Severe Brain Injury

  • K. H. Chan
  • S. C. P. Ng


The principal goal of management of patients with severe brain injury is to provide an adequate supply of oxygen as well as other important metabolites to the brain. Cerebral ischemia develops when oxygen delivery is impaired. Important causes of brain ischemia include raised intracranial pressure (ICP), decreased cerebral perfusion pressure (CPP), hypotension, and hypoxia.


Cerebral Blood Flow Cerebral Perfusion Pressure Cerebral Blood Volume Cerebral Autoregulation Severe Brain Injury 
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Copyright information

© Springer-Verlag Tokyo 1995

Authors and Affiliations

  • K. H. Chan
    • 1
  • S. C. P. Ng
    • 1
  1. 1.Division of Neurosurgery, Department of Surgery, Queen Mary HospitalThe University of Hong KongHong Kong

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