The Optimal Cerebral Perfusion Pressure for Management of Patients with Severe Brain Injury
The principal goal of management of patients with severe brain injury is to provide an adequate supply of oxygen as well as other important metabolites to the brain. Cerebral ischemia develops when oxygen delivery is impaired. Important causes of brain ischemia include raised intracranial pressure (ICP), decreased cerebral perfusion pressure (CPP), hypotension, and hypoxia.
KeywordsCerebral Blood Flow Cerebral Perfusion Pressure Cerebral Blood Volume Cerebral Autoregulation Severe Brain Injury
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