Abstract
Several lines of evidence suggest that hepatitis C virus (HCV) can infect peripheral blood mononuclear cells (PBMCs) in persistently infected individuals on the basis of specific detection of negative-strand hepatitis C virus (HCV) RNA in PBMCs by reverse transcription-polymerase chain reaction (RT-PCR) and in situ hybridization [1–5]. However, direct information on the pathogenic implication of HCV infection of PBMCs is limited.
Keywords
- Peripheral Blood Mononuclear Cell
- Hypervariable Region
- Predominant Clone
- Pathogenic Implication
- Distinct Amino Acid Sequence
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1999 Springer-Verlag Tokyo
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Hino, K., Okuda, M., Korenaga, M., Yamaguchi, Y., Katoh, Y., Okita, K. (1999). Different Quasispecies of Hepatitis C Virus in Human Serum, Peripheral Blood Mononuclear Cells, and Liver. In: Okita, K. (eds) HCV and Related Liver Diseases. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68488-6_2
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DOI: https://doi.org/10.1007/978-4-431-68488-6_2
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68490-9
Online ISBN: 978-4-431-68488-6
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