Serotonin-2A Receptor Function in Affective Disorders
Serotonin (5-hydroxytryptamine, 5-HT) has a significant, but certainly not exclusive, role in the core behaviors that are disturbed in affective disorders (e.g., mood, sleep, sexual activity, appetite, circadian and seasonal rhythms, neuroendocrine function, body temperature, motor activity, and cognitive function (Meltzer and Lowy 1987). There has been especially extensive interest in central 5-HT2 receptor dysfunction as an important factor in the etiology of affective disorders.
KeywordsBipolar Disorder Depressed Patient Affective Disorder Suicide Victim Bioi Psychiatry
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