Clinical Analysis of Glioma: Ependymoma

  • M. Kitahara


Ependymoma is a localized tumor and is known to be a glioma that can be completely resected. However, such tumors are often deep-seated near the ventricles, histologically malignant, or show spinal dissemination; it is not unusual for appropriate therapy to be uncertain and the prognosis poor. The results of a national survey on brain tumors in Japan [2.8] has indicated that the prognosis in ependymoma is not good, with the 5-year survival rate for intracranial ependymoma being 44.5% and that for malignant ependymoma 26.5%.


Fourth Ventricle Spinal Dissemination Malignant Meningioma Choroid Plexus Papilloma Anaplastic Ependymoma 
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  1. 1.
    Áfra D, Müller W, Slowik F, Wilcke O, Budka H, Turoczy L (1983) Supratentorial lobal ependymomas: Reports on the grading and survival periods in 80 cases, including 46 recurrences. Acta Neurochirurgica 69:243–251PubMedCrossRefGoogle Scholar
  2. 2.
    Barone BA, Elvidge AR (1970) Ependymomas: a clinical survey. J Neurosurg 33:428–438PubMedCrossRefGoogle Scholar
  3. 3.
    Bloom HJG (1982) Intracranial tumors: response and resistance to therapeutic endeavors, 1970–1980. Int J Radiat Oncol Biol Phys 8:1083–1113PubMedGoogle Scholar
  4. 4.
    Bouchard J, Peirce CB (1960) Radiation therapy in the management of neoplasms of the central nervous system, with a special note in regard to children: twenty years experience, 1939–1958. Am J Roentgenol 84:610–628Google Scholar
  5. 5.
    Chin HW, Maruyama Y, Markesbery W, Young AB (1982) Intracranial ependymoma. Cancer 49:2276–2280PubMedCrossRefGoogle Scholar
  6. 6.
    Coulon RA, Till K (1977) Intracranial ependymomas in children: a review of 43 cases. Child’s Brain 3:154–168PubMedGoogle Scholar
  7. 7.
    Cox DR (1972) Regression model and life tables. JR Stat Soc (B) 34:187–220Google Scholar
  8. 8.
    Cushing H (1932) Intracramial tumors. Notes upon a series of two thusand verified cases with surgical mortality, percentages pertaining thereto. Charles C Thomas, Springfield, IL, p 56Google Scholar
  9. 9.
    Dohrman GJ, Farwell JR, Flannery JT (1976) Ependymomas and ependymoblastomas in children. J Neurosurg 45:273–283CrossRefGoogle Scholar
  10. 10.
    Fokes EC Jr, Earle KM (1969) Ependymomas: clinical and pathological aspects. J Neurosurg 30: 585–594PubMedCrossRefGoogle Scholar
  11. 11.
    Glanzmann CH, Horst W, Schiess K, Friede R (1980) Considerations in the radiation treatment of intracranial ependymoma; prognosis in 24 own cases and results in published series after different techniques of radiation treatment. Strahlentherapie 156:97–101PubMedGoogle Scholar
  12. 12.
    Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457–481CrossRefGoogle Scholar
  13. 13.
    Katakura R, Ohara H, Sakurai Y (1978) Malignant meningioma following irradiation therapy for ependymoma, a case report. Neurol Surg 6:935–939 (in Japanese)Google Scholar
  14. 14.
    Kim YH, Fayos J (1977) Intracranial ependymomas. Radiology 124:805–808PubMedGoogle Scholar
  15. 15.
    Kricheff II, Becker M, Schneck SA, Taveras JM (1964) Intracranial ependymomas: a study of survival in 65 cases treated by surgery and irradiation. Am J Roentogenol 91:167–175Google Scholar
  16. 16.
    Mabon RF, Svien HJ, Kernohan JW, Craig W Mck (1949) Proceedings of the staff meetings of the Mayo Clinic. 24:65–71PubMedGoogle Scholar
  17. 17.
    MeiLiu H, Boggs J, Kidd J (1976) Ependymomas of childhood, child’s Brain 2:92–110Google Scholar
  18. 18.
    Mork S J, Loken AC (1977) Ependymoma: a follow-up study of 101 cases. Cancer 40:907–915PubMedCrossRefGoogle Scholar
  19. 19.
    Oi S, Raimondi AJ (1980) Brain tumors in infants and children—Factors affecting prognosis: I Ependymoma. Neurol Surg 8:1049–1055 (in Japanese)Google Scholar
  20. 20.
    Phillips TL, Sheline GE, Boldrey E (1964) Therapeutic consideration in tumors affecting the central nervous system: ependymomas. Radiology 83:98–105PubMedGoogle Scholar
  21. 21.
    Read G (1984) The treatment of ependymoma of the brain or spinal canal by radiotherapy: A report of 79 cases. Clin Radiol 35:163–166PubMedCrossRefGoogle Scholar
  22. 22.
    Richmond JJ (1953) Radiotherapy of intracranial tumors in children. J Fac Radiologists 4:180–189CrossRefGoogle Scholar
  23. 23.
    Ringertz N, Reymond A (1949) Ependymomas and choroid plexus papillomas. J Neuro-pathol Exp Neurol 8:355–380Google Scholar
  24. 24.
    Salazar OM, Rublin P, Bassano D, Marcial V (1975) Improved survival of patients with intracranial ependymomas by irradiation: dose selection and field extension. Cancer 35:1563–1573PubMedCrossRefGoogle Scholar
  25. 25.
    Salazar OM, Castro-Vita H, Van Houtte P, Rubin P, Aygun C (1983) Improved survival in cases of intracranial ependymoma after radiation therapy. Later report and recommendations. J Neurosurg 59:652–659PubMedCrossRefGoogle Scholar
  26. 26.
    Sheline CE (1975) Radiation therapy of tumors on the central nervous system in childhood. Cancer 35:957–964PubMedCrossRefGoogle Scholar
  27. 27.
    Svien HJ, Mabon RF, Kernohan JW, Craig W Mck (1953) Ependymoma of the brain: pathologic aspects. Neurology 3:1–15PubMedGoogle Scholar
  28. 28.
    The committee of the brain tumor registry in Japan (1984) Brain tumor registry in Japan, vol. 5. Japanese Ministry of Health and Welfare, TokyoGoogle Scholar

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© Springer-Verlag Tokyo 1988

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  • M. Kitahara

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