Epidemiology and Statistical Analysis of Gliomas
There have been a great many studies on the epidemiology and statistical analysis of brain tumors [1,4–6, 9, 18,22], but most of them have been concerned with tumors of the entire central nervous system. There have been few detailed studies on gliomas alone. One reason for the scarcity of such work is the fact that, starting with the classification of Bailey and Cushing , several classification schemes have been devised [11, 17, 25–27] based upon various criteria—often by the degree of malignancy, as seen in the Kernohan and Say re classification . No unified schema has yet been developed. Schoenberg has emphasized that when undertaking an epidemiological investigation the most important factor is the classification of distinct disease entities . For both epidemiological study and analysis of operative results, if uniformity of the histological classification has not been achieved, it is impossible to make use of the survey results. International uniformity of the histological classification is all the more essential because the incidence of glioma is low and the number of cases treated at any given institute is small.
KeywordsAnaplastic Astrocytoma Pilocytic Astrocytoma Epidermal Growth Factor Receptor Gene Rous Sarcoma Virus Gliomatosis Cerebri
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- 2.Armstrong RM, Hanson CW (1969) Familial gliomas. J Neurol 19:1061–1063Google Scholar
- 3.Bailey P, Cushing H (1926) A classification of the tumors of the glioma group on a histologic basis with a correlated study of prognosis. Lippincott, PhiladelphiaGoogle Scholar
- 11.Kernohan JW, Sayre GP (1952) Tumors of the central nervous system. In: Atlas of tumor pathology, fasc 35. Armed Forces Institute of Pathology, Washington DCGoogle Scholar
- 17.Rubinstein LJ (1979) Tumors of the central nervous system. In: Atlas of tumor pathology, 2nd series, fasc 6. Armed Forces Institute of Pathology, Washington DCGoogle Scholar
- 20.Suzuki J, Iwabuchi T, Kanaya H, Kodama N, Kowada M, Nakai A, Tanaka R (1984) Tohoku Brain Tumor Registry, vol. 1 Committee of Tohoku Brain Tumor Registry Sendai JapanGoogle Scholar
- 22.The committee of brain tumor registry in Japan (1984) Brain Tumor Registry in Japan, vol. 5 The Ministry of Welfare in JapanGoogle Scholar
- 24.Westermark B, Nister M, Heldin CH (1985) Growth factors and oncogenes in human malignant glioma. Neurol Clinics 3: 785–799Google Scholar
- 26.Zulch KJ, Wechsler W (1968) Pathology and classification of gliomas. Basel New York (Progr neurol surg, vol. 2, pp 1–84)Google Scholar