Advertisement

Spatiotemporal Changes in Gap Junctional Communication During Retinal Development and Regeneration of Adult Newt

  • Takehiko Saito
  • Hanako Oi
  • Yumiko Umino
  • Akiko Fukutomi
  • Chikafumi Chiba
  • Osamu Kuwata
Conference paper
  • 144 Downloads
Part of the Keio University International Symposia for Life Sciences and Medicine book series (KEIO, volume 11)

Abstract

Gap junctions are one of the pathways mediating cell-to-cell communications in many biological systems. They form channels allowing ions and small molecules to pass from one cell to another. The presence of gap junctional communication in the vertebrate central nervous system (CNS) including the retina has been well documented by electrical measurements as well as dye coupling. In adult vertebrate retinas, gap junctions often form electrical synapses that mediate the rapid synaptic transmission. However, it has been also reported that gap junctions are present abundantly between cells that are not electrically excitable in the early developmental retina. Functional role(s) of such gap junctions are largely unknown.

Key words

Gap junction Connexin43 Progenitor cell 

Copyright information

© Springer-Verlag Tokyo 2003

Authors and Affiliations

  • Takehiko Saito
    • 1
  • Hanako Oi
    • 1
  • Yumiko Umino
    • 1
  • Akiko Fukutomi
    • 1
  • Chikafumi Chiba
    • 1
  • Osamu Kuwata
    • 1
  1. 1.Institute of Biological SciencesUniversity of TsukubaTsukubaJapan

Personalised recommendations