Pathogenesis of Cholesteatoma

  • Tamotsu Morimitsu


There are several different theories that attempt to explain the etiology of cholesteatoma. The three most popular original theories are (1) the retraction pocket theory states that cholesteatoma forms by accumulation of debris in retraction pockets arising from Shrapnell’s membrane or from the adhered pars tensa, caused by occlusion of the eustachian tube (Bezold 1908); (2) the migration theory states that squamous epithehum which has migrated into the middle ear through a perforated tympanic membrane proliferates there (Habermann 1889); and (3) the metaplastic theory states that squamous metaplasia of the middle ear mucosa forms following chronic inflammation (Wendt 1873).


Otitis Medium Acute Otitis Medium Eustachian Tube Chronic Otitis Medium Retraction Pocket 


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Copyright information

© Springer-Verlag Tokyo 1997

Authors and Affiliations

  • Tamotsu Morimitsu
    • 1
  1. 1.Miyazaki Medical CollegeMiyazakiJapan

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