Secondary Flow and Atherogenesis
Hemodynamic factors appear to affect atherosclerosis. Secondary flow in the aorta was studied by subjecting rabbits to constant pressure perfusion fixation and observing endothelial arrangement by scanning electron microscopy.
Endothelial orientation is oblique in a lateral-medical direction on the dcrsal and ventral sides in the ascending, arch and descending segments. The direction of blood flow in these regions is oblique. This oblique flow is thought to be the result of longitudinal flow and secondary flow. The oblique orientation of the endothelial cells suggests the existence of secondary flow.
KeywordsLongitudinal Axis Lateral Side Secondary Flow Ventral Side Medial Side
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