The Role of Haemodynamics in the Proliferative Lesions of Atherosclerosis

  • W. E. Stehbens


Atherosclerosis, a degenerative disease of blood vessels, is universal in man and is not species-specific. Popular theories of its aetiology are only concerned with some aspects of the disease and do not explain the pathogenesis and the complications. Present evidence substantiates the view that the topography of the disease can be explained by local haemodynamic factors and indicates also that haemodynamically-induced vibrational stress is capable of producing the disease and its complications even in the absence of elevated serum lipids. This fatigue hypothesis is the most plausible explanation of the disease and its complications.


Intracranial Aneurysm Intimal Proliferation Stock Diet Daughter Branch Carotid Siphon 
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Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • W. E. Stehbens
    • 1
  1. 1.Department of PathologyWellington School of Medicine and the Malaghan Institute of Medical ResearchWellington 2New Zealand

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