Observations on Carotid Bifurcation Atherosclerosis in Human Cadavers
The atherosclerotic changes in the carotid bifurcation were examined in 70 Japanese and 73 German cadavers. Initially, a fatty streak or dot appeared in the carotid sinus and/or on the anterior side of the common carotid artery. Further progression occurred predominantly in the carotid sinus, resulting in a localized atheromatous plaque. Finally an atheromatous plaque was formed all around the bifurcation. The following speculation was made from observations of many carotid bifurcations; the accumulation of fatty streaks on the anterior surface of the common carotid artery results in an atheromatous plaque in the carotid sinus analogous to accumulation of sand on a sandbank in a river. This concept may be useful in understanding the progression of atheromatous plaques.
KeywordsCarotid Artery Common Carotid Artery External Carotid Anterior Surface Carotid Bifurcation
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- (1).Giddens DP, Zarins CK, Glagov S, Bharadvaj BK and Ku DN (1983) Flow and atherogenesis in the human carotid bifurcation. In: Schettler G, Nerem RM, Schmid-Schönbein H, Mörl H, Diehm C (eds) Fluid Dynamics as a Localizing Factor for Atherosclerosis. Springer-Verlag, Berlin Heidelberg New York Tokyo, pp 38–45CrossRefGoogle Scholar