Flow Studies in True-to-Scale Models of Human Renal Arteries

  • D. Liepsch
  • A. Poll
  • S. Moravec
Conference paper


The flow behavior in rigid and elastic models of human renal arteries have been studied using glycerol-water and a blood-like viscoelastic fluid. The studies were done at steady and pulsatile flow. The differences between Newtonian and non-Newtonian blood-like fluids were especially visible at unsteady flow in the flow separation zones. Here the flow consists of high local convective parts. The studies were limited to the abdominal aorta downstream of the renal arteries where most sclerotic plaques are formed. The flow was visualized by using dyes and a birefringent solution. The disturbed flow can easily be localized with these methods. The velocity profiles were measured with a laser-Doppler-anemometer. The velocity gradients increased in the pulsatile flow between the main forward and reverse flow. These lead to higher shear stresses which can activate blood platelets and change the surface of the membrane of red cells. We found about a 15% flow increase during pulsatile flow with a representative Reynolds number of 250 for the Polyacrylamide mixture compared to glycerol-water.


Renal Artery Abdominal Aorta Velocity Fluctuation Pulsatile Flow Shear Rate Range 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    Karino T, Kwong HB, Goldsmith HL (1979) Biorheology 16: 231–248.PubMedGoogle Scholar
  2. [2]
    Ku DN, Giddens DP (1983) Atherosclerosis 3: 31–39.Google Scholar
  3. [3]
    Liepsch D, Zimmer R (1978) Biomed Tech 23: 227–230.CrossRefGoogle Scholar
  4. [4]
    Liepsch D (1986) Stroemungsuntersuchungen an Modellen menschlicher Blutgefaess Systeme. Fortschrittberichte VDI, Reihe 7: Stroemungstechnik Nr. 113, VDI-VerlagGoogle Scholar
  5. [5]
    Liepsch D (1984) Biorheology 23: 395–433.Google Scholar
  6. [6]
    Moravec ST (1986) Stroemungsuntersuchungen mit newtonschen und viskoelastischen Fluessigkeiten in Modellen menschlicher Nierenarterien unter Verwendung eines Iaser-Doppler-Anemometers. Ph.D. Thesis TU MuenchenGoogle Scholar
  7. [7]
    Niimi H (1983) Clin Hemorheol 3: 223.Google Scholar
  8. [8]
    Rodkiewicz CM (1981) CISM Courses and Lectures, No. 270, Wien: Springer.Google Scholar
  9. [9]
    Sabbah HN, Hawkins ET, Stein PD (1984) Atherosclerosis 4: 28–33.Google Scholar
  10. [10]
    Stehbens WE (1975) Q J Exp Physiol 60: 181–192.Google Scholar

Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • D. Liepsch
    • 1
  • A. Poll
    • 1
  • S. Moravec
    • 2
  1. 1.Hal B. Wallis Research Facility of the Eisenhower Medical CenterRancho MirageUSA
  2. 2.Institut für Biotechnik u. Fachhochschule MünchenMünchenFederal Republic of Germany

Personalised recommendations