Hearing Preservation on Gentamicin Treatment for Meniere’s Disease

Abstract

Meniere’s disease is characterized by episodic vertigo, fluctuating hearing loss, ear fullness and tinnitus. It may be due to increased pressure in one of the inner ear fluid compartments. Fluid in the inner ear chambers are constantly being produced and absorbed by the circulatory system. Any disturbance in this delicate relationship results in over-production or under-absorption of the fluids. This leads to increased fluid pressure (hydrops) that in turn produces dizziness which is often associated with fluctuating hearing loss and tinnitus. Endolymphatic hydrops is generally accepted as the histopathological finding for Meniere’s disease. However, pathophysiology of Meniere’s disease is still controversial.