Normal Wistar Kyoto ( WKy) rats aged 6, 18, and 24 months were used for evaluation of natural course and aging. Spontaneously hypertensive rats (SHRs) aged 6,9, and 15 months were used for the research on hypertension. Inherited hypercholesterolemic (RICO) rats (Cardona-Sanclemente et al. 1989) aged 10-12, 15, and 18 months were used for the study of arteriosclerosis. Otsuka Long-Evans Tokushima Fatty (OLETF) rats (spontaneously diabetic strain) aged 14 and 17 months were used for the study of diabetes mellitus.


Retinal Vessel Capillary Network Posterior Pole Retinal Vasculature Retinal Capillary 


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Copyright information

© Springer-Verlag Tokyo 2003

Authors and Affiliations

  • Tsugio Amemiya
    • 1
  1. 1.Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical SciencesNagasaki UniversityNagasakiJapan

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