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Ventricular septal defect in Chinese with aortic valve prolapse and aortic regurgitation

  • Hung-Chi Lue
  • Tseng-Chen Sung
  • Shou-Hsien Hou
  • Mei-Hwan Wu
  • Su-Ju Cheng
  • Shu-Hsung Chu
  • Chi-Ren Hung

Abstract

Aortic regurgitation (AR) is one of the most important complications occurring in patients with ventricular septal defect (VSD). It occurred in 1.9%–5.5% of all patients with VSD in Western countries [1–6] but occurred at higher rates, 7.0%–13.1%, in Hawaii [7] and Japan [8, 9], suggesting that a racial difference exists. Aortic valve prolapse might, as proposed by Blumenthal et al. [10] in 1967, precede the development of AR, particularly in patients with subpulmonic VSD. Whether Chinese, like Japanese, are prone to develop aortic valve prolapse and AR is unknown [11]. Controversies still exist regarding the optimal surgical treatment and timing of the operation for such patients due to a paucity of information [1, 5, 12–16]. To clarify these matters, we started in January, 1978 a prospective study to identify the anatomical type of the VSD and to check the integrity and competency of the aortic valves of all infants and children with VSD to be catheterized at the National Taiwan University Hospital. Another 306 patients with VSD who were catheterized from 1970 to 1977 were also reviewed to determine the type of VSD and the integrity and competency of the aortic valve. An analysis of the results of these two studies forms the basis of this report.

Keywords

Aortic Valve Aortic Regurgitation Ventricular Septal Defect Ventricular Septal Defect Bicuspid Aortic Valve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1986

Authors and Affiliations

  • Hung-Chi Lue
    • 1
  • Tseng-Chen Sung
  • Shou-Hsien Hou
  • Mei-Hwan Wu
  • Su-Ju Cheng
  • Shu-Hsung Chu
    • 2
  • Chi-Ren Hung
    • 2
  1. 1.Department of PediatricsNational Taiwan University College of MedicineTaipeiTaiwan, ROC
  2. 2.Department of SurgeryNational Taiwan University College of MedicineTaipeiTaiwan, ROC

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