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PET Measurement of Myocardial Blood Flow

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Regulation of Coronary Blood Flow

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Abstract

Positron emission tomography (PET) has potentials for quantification of regional myocardial blood flow and metabolism in vivo. PET perfusion images can be obtained using N-13 ammonia, a generator-produced rubidium-82, and O-15 water. PET provides higher quality perfusion images than the widely used thallium-201 perfusion images. Therefore, the qualitative PET perfusion study can yield higher sensitivity and specificity for diagnosing coronary artery disease than the thallium-201 imaging. In addition, quantitative analysis of flow reserve by PET may further enhance the identification of a mild coronary perfusion abnormality. The tracers and techniques of PET perfusion imaging as well as the clinical value of PET perfusion study are discussed.

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Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, Kyoto University Faculty of Medicine, Kyoto, 606, Japan

    Junji Konishi

Authors
  1. Nagara Tamaki
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  2. Yoshiharu Yonekura
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  3. Junji Konishi
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Editor information

Editors and Affiliations

  1. Department of Medical Information Sciences, Osaka University Hospital, Osaka, 553, Japan

    Michitoshi Inoue M.D., Ph.D. (Professor) (Professor)

  2. The First Department of Medicine, Osaka University School of Medicine, Osaka, 553, Japan

    Masatsugu Hori M.D., Ph.D. (Assistant Professor) (Assistant Professor)

  3. Department of Pharmacology, Niigata University School of Medicine, Niigata, 951, Japan

    Shoichi Imai M.D., Ph.D. (Professor) (Professor)

  4. Department of Physiology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA

    Robert M. Berne M.D. (Alumni Professor) (Alumni Professor)

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© 1991 Springer Japan

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Tamaki, N., Yonekura, Y., Konishi, J. (1991). PET Measurement of Myocardial Blood Flow. In: Inoue, M., Hori, M., Imai, S., Berne, R.M. (eds) Regulation of Coronary Blood Flow. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68367-4_4

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  • DOI: https://doi.org/10.1007/978-4-431-68367-4_4

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68369-8

  • Online ISBN: 978-4-431-68367-4

  • eBook Packages: Springer Book Archive

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