Principles for Designing Scientific Investigations of Orthopedic Malignancies

  • Masanori Fukushima
Conference paper


Chemotherapy is presently at an investigational stage, and the findings of ordinary clinical practitioners are an integral part of these investigations. Since tumors of the bone or soft tissue are rare, multi-institutional study is indispensable. One example, chemotherapy of osteosarcoma, is reviewed and principles for conducting a clinical investigation are described.


Adjuvant Chemotherapy Clin Oncol Quality Control Process Prospective Randomized Control Study Orthopedic Oncology 
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Copyright information

© Springer Japan 1992

Authors and Affiliations

  • Masanori Fukushima
    • 1
  1. 1.Aichi Cancer CenterNagoya, 464Japan

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