Preliminary Histomorphometric Study on Pathological Grading of Giant Cell Tumors of Bone
Since Jaffe and his associates [1, 2], emphasized the importance of histological grading of giant cell tumor (GCT) of bone and classified them into three grades, benign or low aggressive, more aggressive or malignant, and frankly malignant, most of the orthopedists, radiologists, and pathologists in China adopted this grading system [3–6]. Pathological grading of GCT of bone is a complicated process and different opinions may exist among individual pathologists for the same specimen. However, histopathological observation of GCT of bone is benificial for predicting prognosis, and we attempted to determine the pathological grading of GCT of bone using histomorphometry.
KeywordsStroma Cell Giant Cell Volume Index Giant Cell Tumor Giant Cell Tumor
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