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Limb-Salvage Procedures for Osteosarcoma Using Intraoperative Radiation Therapy

  • Yoshihiko Kotoura
  • Takao Yamamuro
  • Katsuyuki Kasahara
  • Renpei Iwasaki
  • Masaji Takahashi
  • Mitsuyuki Abe
Conference paper

Abstract

The survival rate of patients with osteosarcoma has been improved by advanced diagnostic techniques, the combined use of chemotherapy and radiotherapy, improved operative techniques, and integrated care systems. In the past, these patients were mainly treated by amputation combined with chemotherapy. However, in recent years, increasing advances have been made in limb salvage techniques. Since 1978, we have adopted the use of intraoperative radiation therapy (IORT) for local control of primary lesions of osteosarcoma [1] and of metastatic bone tumors. We describe the method of IORT, its antitumor effect, and clinical results.

Keywords

Antitumor Effect Intramedullary Nailing Limb Salvage Vastus Intermedius Metastatic Bone Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Yamamuro T, Kotoura Y, Kasahara K, Takahashi M, Abe M (1989) Intraoperative radiotherapy and ceramic prosthesis replacement for osteosarcoma. In: Yamamuro T (ed) New developments for limb salvage in musculoskeletal tumors. Springer-Verlag, Tokyo, pp 328–333CrossRefGoogle Scholar
  2. 2.
    Nagashima T, Yamamuro T, Kotoura Y, Takahashi M, Abe M, Nakashima Y (1983) Histological studies of the effect of intra-operative irradiation on osteosarcoma (in Japanese). J Jpn Orthop Assoc 57: 1681–1697Google Scholar
  3. 3.
    Abe M, Takahashi M, Yabumoto E, Tobe T, Mori K (1974) Intraoperative radiotherapy of gastric cancer. Cancer 34: 2034–2041PubMedCrossRefGoogle Scholar

Copyright information

© Springer Japan 1992

Authors and Affiliations

  • Yoshihiko Kotoura
  • Takao Yamamuro
  • Katsuyuki Kasahara
  • Renpei Iwasaki
    • 1
  • Masaji Takahashi
    • 2
  • Mitsuyuki Abe
    • 3
  1. 1.Department of Orthopedic Surgery, Faculty of MedicineKyoto UniversityKyoto, 606Japan
  2. 2.Chest Disease Research InstituteKyoto UniversityKyoto, 606Japan
  3. 3.Department of Radiology, Faculty of MedicineKyoto UniversityKyoto, 606Japan

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