Future Directions in the Management of Malignant Bone Tumors
In spite of the considerable improvements produced by combination chemotherapy, there remain many problems still to be tackled in order to enhance the survival rate of patients with primary malignant bone tumors. There is some evidence that current chemotherapy programs have reached a plateau in their effect on survival, and that further improvements are going to be difficult both to obtain and to detect. This chapter describes some of the remaining problems and discusses some possibilities for advancement. The increasing specialization of the treatment of primary malignant bone tumors has had the advantage that, in many countries, the expertise has been concentrated in a few major centers. This means that national and international collaboration in clinical trials should become easier if agreement can be reached on the nature of the questions to be posed.
KeywordsClin Oncol Pulmonary Metastasis Malignant Bone Tumor Round Cell Tumor Primary Malignant Bone Tumor
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