Advertisement

Schistosomiasis Mansoni—Clinical Features

  • Luiz Caetano Da Silva

Abstract

The human schistosomes or blood flukes are digenetic trematodes belonging to the super-family Schistosomatoidea. The main species of Schistosoma responsible for the clinical forms are mansoni, hematobium and japonicum.

Keywords

Hepatic Artery Portal Hypertension Esophageal Varix Hepatic Coma Digenetic Trematode 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Hillyer GV (1982) Schistosomiasis. In: Hillyer GV, Hopla CE (eds) CRC handbook series in zoonoses, Vol III. CRC, Boca Raton, Florida, pp 177-210Google Scholar
  2. 2.
    Webbe G (1982) The parasites. In: Jordan P, Webbe G (eds) Schistosomiasis. Epidemiology, treatment and control. William Heinemann, London, pp 1–15Google Scholar
  3. 3.
    Bina JC, Prata A (1984) A evolução natural da esquistossomose mansoni em uma área endêmica. In: CEDRE—Centro de Doenças Regionais (ed) Aspectos peculiares da infecção por Schistosoma mansoni. Centro Edit Didat U F Bahia, Salvador, pp 13–33Google Scholar
  4. 4.
    Caetano da Silva L, Pontes JF (1965) Clinical aspects of schistosomiasis mansoni. In Popper H, Schaffner F (eds) Progress in Liver Diseases. Grund and Stratton, New York, pp 243–252Google Scholar
  5. 5.
    Coutinho AD, Domingues ALC (1988) Esquistossomose mansoni. In: Dani R, Castro LP (ed) Gastroenterologia clínica, 2nd edn. Edit Guanabara, Rio de Janeiro pp 1361-1386Google Scholar
  6. 6.
    Prata A (1982) Infection with S. mansoni. In: Jordan P, Webbe G (eds) Schistosomiasis. Epidemiology, treatment and control. William Heinemann, London, pp 105–127Google Scholar
  7. 7.
    Smithers SR, Doenhoff MJ (1982) Schistosomiasis. In: Cohen S, Warren KS (ed) Immunology of Parasitic Infections, 2nd edn. Blackwell, Oxford, pp 527-607Google Scholar
  8. 8.
    Bina JC (1977) Influência da terapêutica específica na evolução da esquistossomose mansoni. Thesis, Faculdade de Medicina Bahia, SalvadorGoogle Scholar
  9. 9.
    Coura JR, Conceição MJ (1981) Correlação entre carga parasitária de S. mansoni e gravidade das formas clínicas em uma comunidade rural de Minas Gerais. Rev Soc Bras Med Trop 14: 93–97CrossRefGoogle Scholar
  10. 10.
    Mies S, Mori T, Larsson E, Rosa P, Jara JG, Santos LF dos, Loscher W, Raia S (1980) A veia cava inferior e as veias supra-hepáticas na esquistossomose hepatoesplênica. Estudo angiográfico. Rev Hosp Clin Fac Med Sao Paulo 35: 136–142PubMedGoogle Scholar
  11. 11.
    Mies S, Mori T, Larsson E, Rosa P, Raia S (1980) Hepatic vein in mansonic schistosomiasis. Angiographic and hemodynamic pattern Gastroenterology 78: A1314Google Scholar
  12. 12.
    Coutinho A (1968) Hemodynamic studies of portal hypertension in schistosomiasis. Am J Med 44: 547–556PubMedCrossRefGoogle Scholar
  13. 13.
    Raia S (1980) Portal hypertension in schistosomiasis. In: Orloff MJ, Stipa S, Ziparo V (eds) Medical and surgical problems of portal hypertension. Academic, London, pp 301–312Google Scholar
  14. 14.
    Bogliolo L (1957) A esplenoportografia na esquistossomose mansônica hepato-esplênica, forma de Symmers. RAMB 2: 263–269Google Scholar
  15. 15.
    Carneiro JL de (1979) A circulação colateral gastroesofágica após desconexão azigoportal. Thesis, Centro Biom Univ Fed Espírito Santo, VitóriaGoogle Scholar
  16. 16.
    Raia S, Mies S, Macedo AL (1985) Portal hypertension in schistosomiasis. Clin Gastroenterol 14: 57–82PubMedGoogle Scholar
  17. 17.
    Mies S, Larsson E, Mori T, Rosa P, Raia S (1980) O sistema porta e as artérias hepática, esplênica e mesentérica superior na esquistossomose hepatoesplênica. Estudo angiográfico. Rev Hosp Clin Fac Med Sao Paulo 35: 121–131PubMedGoogle Scholar
  18. 18.
    Alves CAP, Alves AR, Abreu WN, de Andrade AA (1977) Hepatic artery hypertrophy and sinusoidal hypertention in advanced schistosomiasis. Gastroenterology 72: 126–128PubMedGoogle Scholar
  19. 19.
    Raia S, Mies S, Macedo AL (1984) Surgical treatment of portal hypertension in schistosomiasis. World J Surg 8: 738–752PubMedCrossRefGoogle Scholar
  20. 20.
    Ramos OL, Saad F, Leser WP (1964) Portal hemodynamics and liver cell function in hepatic schistosomiasis. Gastroenterology 47: 241–247PubMedGoogle Scholar
  21. 21.
    Condon RE, Nyhus LM, Chapman ND, Harkins HN (1962) Portal vein and hepatic artery interaction; studies in the isolated, perfused liver. Gastroenterology 43: 547–556PubMedGoogle Scholar
  22. 22.
    da Silveira GSM (1980) Circulação arterial e portal do fígado esquistossomótico após esplenectomia. Thesis, Fac Med Univ Fed Bahia, Salvador, BrasilGoogle Scholar
  23. 23.
    Lyra LG, Rebouças G, Andrade Z (1976) Hepatitis B surface antigen carrier state in hepatosplenic schistosomiasis. Gastroenterology 71: 641–645PubMedGoogle Scholar
  24. 24.
    Strauss E, Lacet CMC (1986) Hepatite e esquistossomose mansonic. In: Caetano da Silva L (ed) Hepatites agudas e crônicas. Ed Sarvier, São Paulo, pp 171-178Google Scholar
  25. 25.
    Warren KS, Rebouças G, Baptista AG (1965) Ammonia metabolism and hepatic coma in hepatosplenic schistosomiasis. Patients studied before and after portocaval shunt. Ann Intern Med 62: 1113–1133PubMedCrossRefGoogle Scholar
  26. 26.
    Katz N, Chaves A, Pellegrino J (1972) A simple device for quantitative stool thick smears technique in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 14: 397–400PubMedGoogle Scholar
  27. 27.
    Mott KE, Dixon H (1982) Collaborative study on antigens for immunodiagnosis of schistosomiasis. Bull WHO 60: 729–753PubMedGoogle Scholar
  28. 28.
    Caetano da Silva L, Hoshino-Shimizu S, Kanamura HY, Strassman PG, Camargo ME, Sette H Jr, Lopes JD, Chamone DAF, Raia S, Silva GR (1975) Serum antibodies changes after chemotherapy of patients with schistosomiasis mansoni. A statistical analysis. Rev Inst Med Trop São Paulo 17: 344–349Google Scholar
  29. 29.
    Caetano da Silva L, Ferri RG (1965) Immunodiffusion studies in human schistosomiasis mansoni. I. Hepatointestinal and hepatosplenic forms. Rev Inst Med Trop Sao Paulo 7: 1–6Google Scholar
  30. 30.
    Pinon JM, Dropsy G (1977) Etude de l’immunité humorale dans la bilharziose humaine. Interêt de l’ELIEDA (enzyme-linked-immuno-electro-diffusion-assay). Bull Soc Pathol Exot Filiales 69: 238–244Google Scholar
  31. 31.
    Jamra M, Maspes V, Meira DA (1964) Types and mechanisms of anemia in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 6: 126–136PubMedGoogle Scholar
  32. 32.
    Manoukian N, Borges DR (1984) Prealbumin, prekallikrein and prothrombin in hepatosplenic schistosomiasis: Increased turnover of the clotting proteins?. Rev Inst Med Trop Sao Paulo 26: 237–240PubMedCrossRefGoogle Scholar
  33. 33.
    Manoukian N, Borges DR (1988) Hypoprothrombinemia in the compensated form of hepatosplenic schistosomiasis: Further studies. Rev Inst Med Trop Sao Paulo 30: 274–280PubMedCrossRefGoogle Scholar
  34. 34.
    Borges DR, Manoukian N, Toledo CF (1987) Protein C deficiency in the compensated form of hepatosplenic schistosomiasis (letter). Braz J Med Biol Res 20: 557–560PubMedGoogle Scholar
  35. 35.
    Borges DR, Pardini DP, Chehter L (1989) Estudo, em portadora da esquistossomose hepatoesplênica, da protrombina e da procalicreína: Efeitos da heparinização e esplenectomia (letter). RAMB 35: 39–40Google Scholar
  36. 36.
    Caefauo da Silva L, Sette H Jr (1978) Pulmonary and renal lesions after oxamniquine in patients with hepatosplenic schistosomiasis mansoni. Gastroenterology 74: A1118Google Scholar
  37. 37.
    Andrade ZA, Andrade SG (1984) Patologia da esquistossomose hepatoesplênica. In: CEDRE— Centro de Doenças Regionais (ed) Aspectos peculiares da infecção por Schistosoma mansoni. Centro Edit Didat U F Bahia, Salvador, pp 103-131Google Scholar
  38. 38.
    Keiner S, Ferreira PR, Dantas A, Lima Filho JFC, Souza AP, Carreiro Jr JCP, Ferraz EM, Silveira M, Coelho ARB, Câmara Neto RD, Domingues LAW (1982) Ligadura de varizes esôfago-gástricas na hipertensão porta esquistossomótica: avaliação de 25 anos. Rev Col Bras Cirurg 9: 140–146Google Scholar
  39. 39.
    Caetano da Silva L, Sette H Jr, Chamone DAF, Sáez-Alquezar A, Punskas JA, Raia S (1975) Further clinical trials with oxamniquine (UK 4271), a new anti-schistosomal agent. Rev Inst Med Trop Sao Paulo 17: 307–311Google Scholar
  40. 40.
    Caetano da Silva L, Zeitune JMR, Rosa-Eid LMF, Lima DMC, Antonelli RH, Christo CH, Sáez-Alquezar A, Carboni AC (1986) Treatment of patients with schistosomiasis mansoni: A doubleblind clinical trial comparing praziquantel with oxamniquine. Rev Inst Med Trop Sao Paulo 28: 174–180CrossRefGoogle Scholar
  41. 41.
    Caetano da Silva L, Sette H Jr, Christo CH, Sáez-Alquezar A, Carneiro CRW, Lacet CM, Ohtsuki N, Raia S (1981) Praziquantel in the treatment of the hepatosplenic form of schistosomiasis mansoni. Arzneimittelforschung 31: 601–603Google Scholar
  42. 42.
    Mies S, Pereira MB, Orlando CD, Sette M, Raia S (1988) Propranolol na prevenção da récidiva de hemorragia digestiva em pacientes com esquistossomose hepatoesplênica. RAMB 34: 24–28Google Scholar
  43. 43.
    Braghirolli Neto O (1988) Fluxo sanguíneo da veia ázigos na esquistossomose hepatoesplênica: Ação do propranolol. Thesis, Faculdade de Medicina da Universidade de São Paulo, São PauloGoogle Scholar
  44. 44.
    Sakai P (1985) Escleroterapia endoscópica das varizes sangrantes do esôfago em pacientes esquistossomóticos. Thesis, Faculdade de Medicina da Universidade de São PauloGoogle Scholar
  45. 45.
    Caetano da Silva L, Strauss E, Gayotto LCC, Mies S, Macedo AL, da Silva AT, Silva EF, Lacet CMC, Antonelli, RH, Silva AO, Fermanian J, Chamone DAF, Foster S, Sáez-Alquezar A, Raia A, Raia S (1986) A randomized trial for the study of the elective surgical treatment of portal hypertension in mansonic schistosomiasis. Ann Surg 204: 148–153CrossRefGoogle Scholar
  46. 46.
    Strauss E (1989) Hipertensão portal esquistossomótica: Análise evolutiva de intercorrências clínicas, dados endoscópicos e laboratoriais em estudo randomizado comparando três tipos de cirurgia. Thesis, Fac Med Ribeirão Preto—USP, Ribeirão Preto, BrasilGoogle Scholar
  47. 47.
    Caetano da Silva L, Godoy A, Mendes FT, Leite GM, Pontes JF (1960) Indirect reacting hyperbilirubinemia after portosystemic shunt; its relation to other complications. Gastroenterology 39: 605–614Google Scholar
  48. 48.
    Abrantes WL, Carvalho MA, Rabelo GD, Drumond DAF (1983) Anastomose esplenorrenal seletiva profilática na forma hepatoesplênica da esquistossomose. Experiência de 74 casos. RAMB 29: 160–162Google Scholar
  49. 49.
    Caetano da Silva L, Barone AA, Cavalcanti TRU, Pontes JF (1968) Postportacaval shunt syndrome. A study based on 16 patients with liver cirrhosis and on 33 patients with hepatosplenic mansonian schistosomiasis. In: MaRkoff MG (ed) The therapy of portal hypertension. Georg Thime, Stuttgart, pp 176-178Google Scholar
  50. 50.
    Caetano da Silva L, Jamra MA, Maspes V, Pontes JF, Pieroni R, Cintra ABU (1963) Pathogenesis of indirect reacting hyperbilirubinemia after porta-caval anastomosis. Gastroenterology 44: 117–124Google Scholar
  51. 51.
    Strauss E, Gayotto LCC, Antonelli R, Deperon S, Cabral GL, Raia S (1986) Systemic surgical shunts and splenomegaly as causes of haemolysis in portal hypertension in mansonic schistosomiasis. Evaluation through serum levels of haptoglobin, hemopexin and bilirubin. J Hepatol 2: 340–350PubMedCrossRefGoogle Scholar
  52. 52.
    Hassab MA (1967) Gastroesophageal decongestion and splenectomy in the treatment of esophageal varices in bilharzial cirrhosis: Further studies with a report on 355 operations. Surgery 61: 169–176PubMedGoogle Scholar
  53. 53.
    Haddad CM, Chacon JP, Herani Filho B, Kobata C, Figueira A (1981) Desvascularização gastroesofágica e esplenectomia no tratamento de varizes esôfago-gástricas. Rev Col Bras Cirurg 8: 293–297Google Scholar

Copyright information

© Springer Japan 1991

Authors and Affiliations

  • Luiz Caetano Da Silva
    • 1
  1. 1.Department of GastroenterologyUniversity of São Paulo-School of MedicineSão PauloBrazil

Personalised recommendations