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Radionuclides in Hemodynamic Investigations

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Portal Hypertension

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Abstract

Radionuclides have long been utilized in the study of portal hemodynamics. Some of the early procedures were invasive, requiring puncture of the spleen or catheterization of the portal and hepatic veins, but more recent techniques are mostly noninvasive. However, the advent of realtime ultrasonography and Doppler flowmetry has largely reduced the demand for studies which use radioactive substances. The purposes of the use of radionuclides were to determine the flow speed in portal circulation, functional flow volume, relative flow volume of the arterial and portal circulation to the liver, degree and route of portal systemic shunting, etc. The reported methods and the radionuclides which were used vary, but from the practical point of view, they may be divided according to the route of administration, specifically, intravenous administration, intrasplenic injection, transcatheter administration, rectal and intestinal instillation, and combinations of these approaches. An analysis of the physicochemical properties of various radionuclides used, such as the half-life, gamma ray energy, etc., and of the counting and imaging instruments are beyond the scope of this chapter and will not be discussed here.

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Authors and Affiliations

  1. Department of Medicine, Chiba University School of Medicine, Chiba, 280, Japan

    Kunio Okuda

  2. Department of Medicine III, Osaka City University Medical School, Osaka 545, Japan

    Susumu Shiomi

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  1. Kunio Okuda
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  2. Susumu Shiomi
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Editors and Affiliations

  1. Department of Medicine, Chiba University Hospital, Inohana 1-8-1, Chiba, 280, Japan

    Kunio Okuda M.D., Ph.D. (Professor) (Professor)

  2. Department of Hepatology, Hopital Beaujon, 92118, Clichy, France

    Jean-Pierre Benhamou M.D. (Professor) (Professor)

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© 1991 Springer Japan

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Okuda, K., Shiomi, S. (1991). Radionuclides in Hemodynamic Investigations. In: Okuda, K., Benhamou, JP. (eds) Portal Hypertension. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68361-2_14

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  • DOI: https://doi.org/10.1007/978-4-431-68361-2_14

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68363-6

  • Online ISBN: 978-4-431-68361-2

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