Liver Transplantation in the Treatment of Liver Cancer

  • Shunzaburo Iwatsuki
  • Thomas E. Starzl


The treatment of choice for hepatic malignancy has been total surgical removal of tumor(s). Ex-tensive liver resection such as right and left trisegmentectomies can now be performed with an operative mortality of less than 5% [1]. Five-year survival of primary liver malignancy after subtotal liver resection has been as high as 46% [1]. On the other hand, the prognosis of liver cancer which cannot be treated with the conventional technique of subtotal liver resection because of extensive hepatic involvement of tumors or coexisting nonneoplastic liver disorders has been quite poor. Total hepatectomy with hepatic replacement (orthotopic liver transplantation) is, at least in concept, an ideal approach for the “unresectable” liver cancer.


Liver Transplantation Orthotopic Liver Transplantation Biliary Atresia Bile Duct Cancer Bile Duct Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Japan 1987

Authors and Affiliations

  • Shunzaburo Iwatsuki
  • Thomas E. Starzl
    • 1
  1. 1.Department of SurgeryUniversity of Pittsburgh Health Center, University of PittsburghPittsburghUSA

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