Ultrasonography in the Diagnosis of Hepatic Tumor

  • Masao Ohto
  • Masaaki Ebara
  • Kunio Okuda


Great progress has been made in the diagnosis of space-occupying lesions of the liver with the advent of real-time ultrasonography (US) [1,2]. US is now indispensable in the detection of small lesions such as minute HCC [3–5]. The ultrasonograph has continuously been improved for better resolution and fewer artefacts. The more recent development of the convex-type real-time probe has significantly reduced the dead angle for the linear probe in the right hepatic lobe immediately below the diaphragm. Although large-mass lesions pose no difficulty in US diagnosis, a new problem has arisen with improved resolution of the transducer, namely the differentiation between small HCC and benign hyperplastic nodules [6–8]. In this chapter, we will discuss mainly US diagnosis of hepatic mass lesions and its significance in the clinical setting.


Hepatic Tumor Tumor Thrombus Cavernous Hemangioma Hyperplastic Nodule Acoustic Shadow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Cooperberg PL, Burhenne HJ (1980) Real-time ultrasonography. Diagnostic technique of choice in calculous gallbladder disease. N Engl J Med 320:1277–1279CrossRefGoogle Scholar
  2. 2.
    Okuda K (1981) Advances in hepatobiliary ultrasonography. Hepatology 1:662–671PubMedCrossRefGoogle Scholar
  3. 3.
    Shinagawa T, Ohto M, Kimura K, Tsunetomi S, Morita M, Saisho H, Tsuchiya Y, Saotome N, Karasawa E, Miki M, Ueno T, Okuda K (1984) Diagnosis and clinical features of small hepatocellular carcinoma with emphasis on the utility of real-time ultrasonography. Gastroenterology 86: 495–502PubMedGoogle Scholar
  4. 4.
    Ebara M, Ohto M, Shinagawa T, Sugiura N, Kimura K, Matsutani S, Morita M, Saisho H, Tsuchiya Y, Okuda K (1986) Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis. A study in 22 patients. Gastoroenterology 90:289–298Google Scholar
  5. 5.
    Okuda K (1986) Early recognition of hepatocellular carcinoma. Hepatology 6:729–738PubMedCrossRefGoogle Scholar
  6. 6.
    Arakawa M, Sugihara S, Kenmochi K, Kage M, Nakashima T, Nakayama T, Tashiro S, Hiraoka T, Suenaga M, Okuda K (1986) Small mass lesions in cirrhosis: transition from benign ade-nomatous hyperplasia to hepatocellular carcinoma? J Gastroenterol Hepatol 1: 3–14CrossRefGoogle Scholar
  7. 7.
    Okuda K (1986) What is the precancerous lesion for hepatocellular carcinoma? J Gastroenterol Hepatol 1:79–85CrossRefGoogle Scholar
  8. 8.
    Arakawa M, Kage M, Sugihara S, Nakashima T, Suenaga M, Okuda K (1986) Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases. Gastroenterology 91:198–208PubMedGoogle Scholar
  9. 9.
    Ohto M, Ono T, Tsuchiya Y, Saisho H, Kimura K (1985) Ultrasound diagnosis in gastroenterology. Igaku-shoin, TokyoGoogle Scholar
  10. 10.
    Sugiura N, Ohto M, Kimura K, Ebara M, Okuda K (1986) Imaging diagnosis of portal tumor thrombosis and its pathophysiology in hepatocellular carcinoma. Jpn J Gastroenterol 83:2151–2160Google Scholar
  11. 11.
    Okuda K, Musha H, Nakajima Y, Kubo Y, Shimokawa Y, Nagasaki Y, Sawa Y, Jinnouchi S, Kaneko T, Obata H, Hisamitsu T, Motoike Y, Okazaki M, Sakamoto K, Nakashima T (1977) Clinicopathological features of encapsulated hepatocellular carcinoma. A study of 26 cases. Cancer 40:1240–1245PubMedCrossRefGoogle Scholar
  12. 12.
    Shinagawa T, Ohto M, Kimura K, Matsutani S, Kimura M, Unozawa T, Ukaji H, Tsunetomi S, Nakano T, Morita M, Saisho H, Tsuchiya Y, Ono T, Okuda K (1981) Ultrasonographic features of hepatocellular carcinoma. Correlation with histopathology. Jpn J Gastroenterol 78:2402–2410Google Scholar
  13. 13.
    Nakashima T, Okuda K, Kojiro M, Jimi A, Yamaguchi R, Sakamoto K, Ikari T (1983) Pathology of hepatocellular carcinoma in Japan. 232 consecutive cases autopsied in ten years. Cancer 51:863–877PubMedCrossRefGoogle Scholar
  14. 14.
    Ohto M, Karasawa E, Tsuchiya Y, Kimura K, Saisho H, Ono T, Okuda K (1980) Ultrasonically guided percutaneous contrast medium injection and aspiration biopsy using a real-time puncture transducer. Radiology 136:171–176PubMedGoogle Scholar

Copyright information

© Springer Japan 1987

Authors and Affiliations

  • Masao Ohto
  • Masaaki Ebara
  • Kunio Okuda
    • 1
  1. 1.First Department of MedicineChiba University School of MedicineInohana, Chiba, 280Japan

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