Advertisement

Current Status of the Registration of Familial Adenomatous Polyposis at the Polyposis Center in Japan

  • Takeo Iwama
  • Yoshio Mishima
  • Joji Utsunomiya

Abstract

The Polyposis Center of Japan had registered 970 cases and 631 families of familial adenomatous polyposis (FAP) up to Oct. 1989. The fusion of families which were registered independently from different institutes was recognized in 104 (16.5%) families. Our survey revealed 1738 affected persons and 4475 persons at risk as carrier of the FAP gene. The frequency of cancer was less in the call-up cases (21%) than the proband cases (60%). Periampullary carcinoma and desmoid tumor were the two most serious extra colonic malignancies. We need to pay attention to the bile duct and to development of desmoid tumor after colo-rectal operation.

Keywords

Familial Adenomatous Polyposis Desmoid Tumor Familial Adenomatous Polyposis Patient Familial Polyposis Coli Duodenal Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1).
    Aioi H, Utunomiya J (1987) A follow up study for adenomatosis coli. Gastroent Endoscopy 29(11) 2701–2703. (summary in English)Google Scholar
  2. 2).
    Hirokawa M, Manabe T, Hino K. (1988) Ampullary carcinoma in Gardner’s syndrome. Jpn J Clin Oncol. 18(1):43–50.PubMedCrossRefGoogle Scholar
  3. 3).
    Hishiki S, Baba S, Mitutani K, Morioka S, Nakamura S, Sakaguchi S (1985) Cancer of the papilla of Vater associated with familial polyposis coli, report of a case. Ito Cho (Stomach and Intestine) 20(9):1027–1032. (summary in English)Google Scholar
  4. 4).
    Hojo M, Marugami Y, Hashimoto T, Kikuyama N, Takano M, Tomita T, Kojima M (1989) A case of colonic polyposis associated with carcinoma of the papilla Vateri. Nihon Shokaki Geka Gakkai Zasshi (J Jpn Soc Gastroent Surg) 22(8): 2126–2129. (in Japanese)CrossRefGoogle Scholar
  5. 5).
    Iida M, Yao T, Ito H, Watanabe H, Shigematu H, Iwashita A (1984) Follow up study of Gastroduodenal lesions in familial adenomatosis coli. Ito Cho (Stomach and Intestine) 19(6): 621–638. (summary in English)Google Scholar
  6. 6).
    Kajihara S, Kinoshita K, Kimura K, Toda S (1986) A case of intestinal polyposis associated with duodenal carcinoma and colonic carcinoma. Nihonn Shokaki Geka Gakkai Zasshi (J Jpn Soc Gastroent Surg) 19(2):256.Google Scholar
  7. 7).
    Kataoka K, Kitagawa N, Toyoda K, Hashimoto Y, Takano N (1989) A case of adenomatosis coli associated with early periampullary carcinoma and early gastric carcinoma. Gastroent Endoscopy 31(8):2238. (in apanese)Google Scholar
  8. 8).
    Kimura H, Nakamura T, Nakano G, Hoshi H, Nakamura M (1982) Development of early cancer of the ampulla of Vater and Duodenal adenoma as seven years after total colectomy which was performed for familial polyposis coli. Ito Cho (Stomach and Intestine) 17(9):983–987. (summary in English)Google Scholar
  9. 9).
    Kuroda A, Kimura W, Wada Y, Sugihara K, Morioka Y (1987) Periampullary carcinoma. Geka Shinryo (Surgical Clinic) 29(3): 323–329. (in Japanese)Google Scholar
  10. 10).
    Ogawa K, Takihara M, Kaji H, Takayasu T, Yamaoka Y, Sugitani A, Hikita J (1983) A case of familial colonic polyposis with duodenal carcinoma. Chubu Gekaigakkai Kiji (Proceeding of the Chubu Surgical Conference) 19:100. (in Japanese)Google Scholar
  11. 11).
    Shimoda T, Suwa T, Hirakata T, Sarashina H, Okui K (1987) A case of familial adenomatosis coli associated with carcinoma of the ampulla Vateri. Nihon Shokaki Geka Gakkai Zasshi (J Jpn Soc Gastroent Surg) 20(12):2796–2799. (in Japanese)CrossRefGoogle Scholar
  12. 12).
    Sugihara K, Muto T, Sawada T, Konishi F, Kamiya J, Morioka Y. A case of Gardner’s syndrome. Ito Cho (Stomach and Intestine) 17(9):977–982. (summary in English)Google Scholar
  13. 13).
    Suzuki N Nabeya K, Hanaoka T, Fukushima H, Kaku C, Kobayashi Y, Oguchi S, Fukuzumi N (1988) A case report of adenomatosis coli associated with carcinoma of the papilla of Vater and fundic gland polyposis. Nihon Shokaki Geka Gakkai Zasshi (J Jpn Soc Gastroent Surg) 21(4);1150–1153. (in Japanese)CrossRefGoogle Scholar
  14. 14).
    Tada M, Kato S, Katagiri H, Okamoto K, Tonouchi M (1987) A case of colonic polyposis which was detected after pancreatico-duocenectomy for periampullary carcinoma. Ibarakikenn Rinnsho Igaku Zasshi (J Ibarakikenn Clin Med) 23:70. (in Japanese)Google Scholar
  15. 15).
    Takano N, Akita Y, Karohji S (1982) A case of adenomatosis coli with colonie cancer complicated with carcinoma of the papilla of Vater. Aomorikenritu Byoin Zasshi (J Aomoriken Hosp) 27(4): 384–389. (in Japanese)Google Scholar
  16. 16).
    Utsunomiya J. (1982) Hereditary gastrointestinal polyposis. Nihon Iji Shinpoo 3044:126–128. (in Japanese)Google Scholar
  17. 17).
    Waddell WR (1975) Treatment of intra-abdominal and abdominal wall desmoid tumors with drugs that affect the metabolism of cyclic 3′,5′ — adenosine monophosphate. Ann Surg 181(3): 299–302.PubMedCrossRefGoogle Scholar
  18. 18).
    Yamanaka Y, Morita S, Hayakawa M, Konn M, Ono K (1988) Adenomatosis coli associated with gastric and ampullar cancer; a case report. Nihon Daicho Kohmon Byo Gakkai Zasshi (J Jpn Soc Colo-Proctology) 41:842–848. (summary in English)CrossRefGoogle Scholar
  19. 19).
    Yoshimi T, Koizumi S, Muto T, Wada Y, Morioka Y (1984) Gardner’s syndrome initially diagnosed as periampullary carcinoma, report of a case. Ito Cho (Stomach and Intestine) 19(12): 1373–1378. (summary in English)Google Scholar

Copyright information

© Springer Japan 1990

Authors and Affiliations

  • Takeo Iwama
  • Yoshio Mishima
  • Joji Utsunomiya

There are no affiliations available

Personalised recommendations