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Ornithine Decarboxylase (ODC) and S-Adenosylmethionine Decarboxylase (AdoMetDC) as Markers of Human Colonic Neoplasia

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Hereditary Colorectal Cancer

Abstract

Increased polyamine biosynthetic activity and raised levels of intra-cellular polyamines are commonly associated with normal, abnormal, and induced proliferative states. Ornithine Decarboxylase and S-adenosylmethionine Decarboxylase are known rate-limiting enzymes in polyamine biosynthesis. Herein, we report results from our group in relation to the activity of these enzymes in colonic neoplasias and their possible role as tumor markers.

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© 1990 Springer Japan

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Herrera, L., Petrelli, N.J., Vial, G. (1990). Ornithine Decarboxylase (ODC) and S-Adenosylmethionine Decarboxylase (AdoMetDC) as Markers of Human Colonic Neoplasia. In: Utsunomiya, J., Lynch, H.T. (eds) Hereditary Colorectal Cancer. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68337-7_40

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  • DOI: https://doi.org/10.1007/978-4-431-68337-7_40

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68339-1

  • Online ISBN: 978-4-431-68337-7

  • eBook Packages: Springer Book Archive

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