Tumor Growth in the Bile Ducts in Hepatocellular Carcinoma

  • Toshiro Nakashima
  • Masamichi Kojiro


Tumor invasion in the bile ducts has been considered rare in HCC and has thus received little attention. Tumor growth in the bile ducts presents a variety of clinical and pathological features [139–141]. In cases in which obstructive jaundice develops, tumor invasion in the hepatic duct and/or common bile duct is frequently found at autopsy. In some cases, invasion by a tumor occurring in the porta hepatis into the adjacent bile duct results in obstructive jaundice as the initial sign, although the HCC itself is still in the early stage. Occasionally, necrotic cancerous tissue in the bile duct lodges at the papilla of Vater, resulting in severe obstructive jaundice. The bile duct is obstructed by hemorrhage and blood clotting in addition to the tumor.


Bile Duct Portal Vein Common Bile Duct Hepatic Duct Obstructive Jaundice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer Japan 1987

Authors and Affiliations

  • Toshiro Nakashima
    • 1
    • 2
  • Masamichi Kojiro
    • 3
  1. 1.School of MedicineKurume UniversityJapan
  2. 2.Research InstituteKurume Koga HospitalKurume, 830Japan
  3. 3.The First Department of PathologyKurume University School of MedicineKurume, 830Japan

Personalised recommendations