Tumor Growth in the Bile Ducts in Hepatocellular Carcinoma
Tumor invasion in the bile ducts has been considered rare in HCC and has thus received little attention. Tumor growth in the bile ducts presents a variety of clinical and pathological features [139–141]. In cases in which obstructive jaundice develops, tumor invasion in the hepatic duct and/or common bile duct is frequently found at autopsy. In some cases, invasion by a tumor occurring in the porta hepatis into the adjacent bile duct results in obstructive jaundice as the initial sign, although the HCC itself is still in the early stage. Occasionally, necrotic cancerous tissue in the bile duct lodges at the papilla of Vater, resulting in severe obstructive jaundice. The bile duct is obstructed by hemorrhage and blood clotting in addition to the tumor.
KeywordsBile Duct Portal Vein Common Bile Duct Hepatic Duct Obstructive Jaundice
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