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The Role of Platelet PAI-1 in the Platelet Rich Plasma Clot Lysis

  • K. Serizawa
  • T. Urano
  • Y. Kozima
  • K. Sakakibara
  • Y. Takada
  • A. Takada
Conference paper

Abstract

Plasminogen activator inhibitor-1 (PAI-1) is physiologically the most important inhibitor of tissue plasminogen activator(t-PA) in plasma(1). It has been suggested that more than 80 to 90% of PAI-1 is stored in the platelet α-granules(2,3). It is not clear, however, whether PAI-1 released from platelet plays an important role in the clot lysis.

Keywords

Antigen Level Plasma Clot Clot Lysis Microtiter Plate Reader Lysis Time 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1993

Authors and Affiliations

  • K. Serizawa
    • 1
  • T. Urano
    • 1
  • Y. Kozima
    • 2
  • K. Sakakibara
    • 1
  • Y. Takada
    • 1
  • A. Takada
    • 1
  1. 1.Dept. of PhysiologyHamamatsu University School of MedicineHamamatsu, ShizuokaJapan
  2. 2.Dept. of MedicineHamamatsu University School of MedicineHamamatsu, ShizuokaJapan

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