The Physiology of the Fibrinolytic System

  • Akikazu Takada
Conference paper


There are many publications on the biochemical aspects of fibrinolysis and therapeutic effects of thrombolytic drugs in occlusive vessel diseases such as myocardial infarction, cerebrovascular thrombosis and venous thrombosis predisposing to pulmonary embolism. Fibrinolysis is, however, physiological phenomenon, which is constantly operating together with the coagulation system to secure the sufficient blood flow to peripheral organs or tissues. We have examined effects of various physiological parameters on the fibrinolytic enzyme system, which will be reviewed together with results reported from other laboratories.


Plasminogen Activator Fibrinolytic Activity Multivessel Disease Fibrinogen Degradation Product Euglobulin Clot Lysis Time 
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Copyright information

© Springer Japan 1993

Authors and Affiliations

  • Akikazu Takada
    • 1
  1. 1.Department of PhysiologyHamamatsu University School of MedicineHamamatsu-shi Shizuoka-kenJapan

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