The Physiology of the Fibrinolytic System
There are many publications on the biochemical aspects of fibrinolysis and therapeutic effects of thrombolytic drugs in occlusive vessel diseases such as myocardial infarction, cerebrovascular thrombosis and venous thrombosis predisposing to pulmonary embolism. Fibrinolysis is, however, physiological phenomenon, which is constantly operating together with the coagulation system to secure the sufficient blood flow to peripheral organs or tissues. We have examined effects of various physiological parameters on the fibrinolytic enzyme system, which will be reviewed together with results reported from other laboratories.
KeywordsPlasminogen Activator Fibrinolytic Activity Multivessel Disease Fibrinogen Degradation Product Euglobulin Clot Lysis Time
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