Abstract
The hemopoietic system is characterized by continuous cell turnover supported by a small populations of cells termed hemopoietic stem cells. It is generally held that multipotential hemopoietic stem cells possess extensive capabilities to self-renew and generate various committed progenitor cells(1). Intercellular communication in the hemopoietic system is mediated by soluble factors called cytokines, whose functional characteristics are now partly explained by their receptor system (2–5). Most cytokine receptor systems consist of a multi-chain complex, a ligand-specific receptor chain (α-chain) and a signal transducing chain (β-chain), the latter of which is often utilized in common by several receptor complexes(2,6).
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© 1996 Springer-Verlag Tokyo
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Nakahata, T. et al. (1996). Ex Vivo Expansion of Human Primitive Hemopoietic Progenitors. In: Ikehara, S., Takaku, F., Good, R.A. (eds) Bone Marrow Transplantation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68320-9_6
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DOI: https://doi.org/10.1007/978-4-431-68320-9_6
Publisher Name: Springer, Tokyo
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Online ISBN: 978-4-431-68320-9
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