Nonsurgical Treatment of AVM: Development of New Liquid Embolization Method
For the recent development of intravascular surgery, it has become possible to treat the arteriovenous malformation (AVM) with percutaneous transluminal embolization. Because it is still difficult to achieve complete cure even with supreme techniques, it seemed to be mandatory to develop an ideal embolization method: superselective balloon catheters and embolization materials. First, we developed a silicone superselective balloon catheter with a floppy tip. Using this catheter, we could catheterize even into perforating branches of middle cerebral or posterior cerebral arteries. Second, we developed a new embolization method using new liquid materials. The materials which are used now consist of conjugated estrogen diluted in 25% ethanol and polyvinyl acetate. In this report, we present the process of the experimental and clinical development.
KeywordsRenal Artery Polyvinyl Acetate Posterior Cerebral Artery Arrow Head Petechial Hemorrhage
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Debrun G, Vinuela F, Fox AJ, Drake CG (1982) Embolization of cerebral arteriovenous malformations with bucrylate: Experience in 46 cases. J Neurosurg 56:615–627PubMedCrossRefGoogle Scholar
Klara PM, George ED, McDonnell DE, Pevsner PH (1985) Morphological studies of human arteriovenous malformations: Effects of isobutyl 2-cyanoacrylate embolization. J Neurosurg 63 421–425PubMedCrossRefGoogle Scholar
Nagamine Y, Komatsu S, Suzuki J (1983) New embolization method using estrogen on microcirculation. Surg Neurol 20:269–275PubMedCrossRefGoogle Scholar
Peregrin JH, Kaspar M, Vanecek R, Belan A (1984) New occlusive agent for therapeutic embolization tested in dogs. Cardiovasc Intervent Radiol 7:97–101PubMedCrossRefGoogle Scholar
Suzuki J, Komatsu S (1981) New embolization method using estrogen for dural arteriovenous malformation and meningiomas. Surg Neurol 16:438–442PubMedCrossRefGoogle Scholar
Suzuki J, Nagamine Y, Takahashi A (1986) New embolization method for inoperable AVMs and vascular rich tumors: Chemical embolization using conjugated estrogen. In: Samii M (ed) Surgery in and around the brain stem and the third ventricle. Springer, Berlin, pp 223–230CrossRefGoogle Scholar
Vinuela F, Fox AJ, Pelz D, Debrun G (1986) Angiographic follow-up of large cerebral AVMs incompletely embolized with isobutyl-2-cyanoacrylate. AJNR 7:919–925PubMedGoogle Scholar