Extracranial-Intracranial Bypass Surgery
Ischemic cerebrovascular disease may be due to embolism, hemodynamic compromise, or small vessel occlusive disease. The extracranial-intracranial (EC-IC) bypass surgery was introduced as a treatment for the hemodynamic causes of cerebral ischemia in 1967. It was based on the logical assumption that the brain is like other organs in the body and that symptoms caused by hypoperfusion to a region can be prevented by increasing the blood flow to that region. In the EC-IC bypass operation, blood flow is improved distal to the occluded or stenotic artery, thereby increasing the perfusion of the ischemic areas.
KeywordsCerebral Blood Flow Cerebral Ischemia Transient Cerebral Ischemia Ischemic Cerebrovascular Disease Stenotic Artery
Unable to display preview. Download preview PDF.
- 5.EC-IC Bypass Study Group (1985) Failure of extracranial-intracranial bypass to reduce the risk of ischemic stroke. Results of an international randomized study. NEJM 313:1191–1200Google Scholar
- 7.Fox AJ, Taylor DW, Peerless SJ (1985) Preexisting collateral pathways: A factor determining success in EC-IC bypass surgery? In: Handa H, Kikuchi H, Yonekawa Y (eds) Anastomoses for cerebral ischemia. Igaku-Shoin, New York, pp 153–157Google Scholar
- 11.Sundt T (1987) Was the international randomized trial of extracranial-intracranial arterial bypass representative of the population at risk? NÉJM 316:816–816Google Scholar