Clinical and Experimental Studies of Leukotrienes in Subarachnoid Hemorrhage
Based on the free radical theory in biological systems, which was proposed in 1973 , actions of lipid peroxides relating to the mechanism of cerebral vasospasm after subarachnoid hemorrhage (SAH) have been investigated . Since leukotrienes (LTs) produced from arachidonic acid are suggested to be involved in the cerebral vasospasm, we studied their sequential changes in CSF and also fatty acid composition of the canine basilar artery in SAH.
KeywordsHigh Performance Liquid Chromatography Fatty Acid Composition Subarachnoid Hemorrhage Cerebral Vasospasm Computerize Tomo
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