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Sequential Changes of Brain Metabolism During Temporary Global Ischemia in the Rat Detected by Simultaneous 1H and 31P MRS

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Advances in Surgery for Cerebral Stroke

Abstract

In vivo magnetic resonance spectroscopy (MRS) provides a noninvasive method for evaluating brain metabolism. Previous studies with 31P MRS have developed techniques for continuous monitoring of phosphate metabolites and intracellular pH (pHi) during ischemia and reperfusion [1]. Furthermore, recent progress has made it possible to monitor brain lactate content quantitatively with 1H MRS [2]. In this study, we utilized a double-tuned surface coil for 1H and 31P MRS. With this recently described method, in vivo 1H and 31P spectroscopy can be carried out simultaneously without retuning or replacement of the coil [3].

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References

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© 1988 Springer Japan

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Shirane, R., Chang, LH., Weinstein, P.R., James, T.L. (1988). Sequential Changes of Brain Metabolism During Temporary Global Ischemia in the Rat Detected by Simultaneous 1H and 31P MRS. In: Suzuki, J. (eds) Advances in Surgery for Cerebral Stroke. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68314-8_117

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  • DOI: https://doi.org/10.1007/978-4-431-68314-8_117

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68316-2

  • Online ISBN: 978-4-431-68314-8

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