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Single Photon Emission Study of Hemodynamic Reserve in Internal Carotid Occlusions

Value of Combined Measurement of Cerebral Blood Flow and Cerebral Blood Volume
  • J. M. Derlon
  • G. Bouvard
  • M. C. Petit
  • J. P. Thenint
  • F. Viader
  • S. Khoury
  • B. Dupuy
  • J. P. Houtteville
Conference paper

Abstract

Unlike carotid endarterectomy which can theoretically prevent both hemodynamic and embolic strokes from atherosclerotic plaques, extracranial-intracranial (EC-IC) bypass is advisable only for lesions determining a chronic decrease of brain perfusion pressure potentially responsible for hemodynamic strokes. Nevertheless, these operations have usually been decided on clinical and angiographic data, and have seldom taken into account objective hemodynamic intracranial parameters. Using positron emission tomography (PET), some authors have shown that permanent disturbances of hemodynamic [6, 7] and metabolic [2] data was a relatively infrequent occurrence in patients with carotid obstructive lesions, but that, in some of them, carotid endarterectomy [6] or EC-IC bypass [10] could reverse these disturbances.

Keywords

Positron Emission Tomography Cerebral Blood Volume Carotid Endarterectomy Internal Carotid Artery Occlusion Internal Carotid Artery Dissection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Barnett HJM, Peerless SJ, Fox AJ, et al. (1985) Failure of extracranial arterial bypass to reduce the risk of ischemic stroke: Results of an International Randomized Trial. N Engl J Med 313:1191–1200CrossRefGoogle Scholar
  2. 2.
    Baron JC, Bousser MG, Laplane D, Comar D, Castaigne P, Kellershorn C (1982) Noninvasive study of cerebral blood flow and oxygen metabolism with positron emission tomography in human cerebral ischemic disorders. In: Rose, FC (ed) Advances in stroke therapy. Raven, New YorkGoogle Scholar
  3. 3.
    Derlon JM, Bouvard G, Hubert P, et al. (1987) Etude hémodynamique des lésions obstructives de l’axe carotidien interne: Intérêt de la mesure couplée du débit et du volume sanguins cérébraux. Rev Neurol 143(1):32–39PubMedGoogle Scholar
  4. 4.
    Derlon JM, Bouvard G, Lechevalier B, et al. (1985) Haemodynamic study of internal carotid artery stenosis and occlusion: Value of coupled measurements of regional cerebral blood and regional cerebral blood volume. In: Meyer JS, Lechner H, Reivich M, Ott E (eds) Cerebral vascular disease, vol. 5, World Federation of Neurology, 12th Salzburg Conference, Excerpta Medica. Elsevier, Amsterdam, pp 170–176Google Scholar
  5. 5.
    Derlon JM, Bouvard G, Lechevalier B, et al. (1986) Haemodynamic study of internal carotid disease: Value of combined measurement of regional cerebral blood flow and blood volume. Ann Vasc. Surg 1:86–97PubMedGoogle Scholar
  6. 6.
    Gibbs JM, Leenders KL, Wise RJS, Jones T (1984) Evaluation of cerebral perfusion reserve in patients with carotid artery occlusion. Lancet 28:182–186CrossRefGoogle Scholar
  7. 7.
    Gibbs JM, Wise RJS, Legg MJ (1983) Progress in emission tomography studies in acute stroke and in patients with carotid occlusion: Pathophysiology of cerebral ischemia and diminished perfusion reserve. In: Progress in stroke research, vol. 2. Pitman, London, pp. 214–226Google Scholar
  8. 8.
    Lassen NA (1983) 133 Xenon tomography of cerebral blood flow in cerebrovascular disease. In: Greenhalgh RM, Rose FC (eds) Progress in stroke research. Pitman, London, pp 197–204Google Scholar
  9. 9.
    Norrving B, Nilson B, Risberg J (1982) rCBF in patients with carotid occlusion: Resting and hypercapnic flow related to collateral pattern. Stroke 13(2):155–162PubMedCrossRefGoogle Scholar
  10. 10.
    Samson Y, Baron JC, Bousser MG, Rey A, Derlon JM, David P, Comoy J (1985) Effects of extra-intracranial arterial bypass on cerebral blood flow and oxygen metabolism in human. Stroke 16:4CrossRefGoogle Scholar

Copyright information

© Springer Japan 1988

Authors and Affiliations

  • J. M. Derlon
    • 1
  • G. Bouvard
    • 1
  • M. C. Petit
    • 1
  • J. P. Thenint
    • 1
  • F. Viader
    • 1
  • S. Khoury
    • 1
  • B. Dupuy
    • 1
  • J. P. Houtteville
    • 1
  1. 1.CHRUCaenFrance

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