Intraoperative Metallic Thrombosis of Carotid-Cavernous Fistula

  • Y. Hosobuchi
Conference paper


It has long been known that red blood cells, white blood cells, and fibrinogen are negatively charged at the normal pH of blood. It is also known that white blood cells and washed platelets migrate to the positive pole in an electrophoretic cell [1, 10]. Thus, the intravascular presence of a metal with a high dissociation constant of positively charged metallic ions, such as Fe2+, Cu2+, and Be2+, should attract these negatively charged intravascular elements to form a thrombus; this reaction should be enhanced by passage of an anodal current through the metal. The earliest attempts to apply this logic to the formation of an intravascular thrombus were made independently by Velpeau in 1831 [11] and Phillips in 1832 [9], who described a method of occluding an artery by introducing needles into the lumen and withdrawing the needles after a thrombus had formed about them. Velpeau [11] and Phillips [9] both suggested that this method might be utilized in the treatment of aneurysms. Moore and Murchison [5] first reported insertion of a permanent wire into an aneurysmal sac to create an intrasaccular thrombus.


Carotid Artery Copper Wire Thoracic Aortic Aneurysm Superior Ophthalmic Vein Bilateral Fistula 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Abramson HA (1924) A possible relationship between the current of injury and the white blood cell in inflammation. Am J Med Sci 167:702–710CrossRefGoogle Scholar
  2. 2.
    Blakemore AH, King BG (1938) Electrothermic coagulation of aortic aneurysms. JAMA 111:1821–1827CrossRefGoogle Scholar
  3. 3.
    Hamby WB (1966) Carotid-cavernous fistula. Charles C Thomas, SpringfieldGoogle Scholar
  4. 4.
    Linton RR, Hardy IB Jr (1952) Treatment of thoracic aortic aneurysms by the “Pack” method of intravascular wiring. N Engl J Med 246:847–855PubMedCrossRefGoogle Scholar
  5. 5.
    Moore CH, Murchison C (1864) On a new method of procuring the consolidation of fibrin in certain incurable aneurysms: With the report of a case in which an aneurysm of the ascending aorta was treated by the insertion of wire. Proc R Med Chir Soc London 4:327–335Google Scholar
  6. 6.
    Mullan S, Beekman, F, Vailati G, et al. (1964) An experimental approach to the problem of cerebral aneurysm. J Neurosurg 21:838–845PubMedCrossRefGoogle Scholar
  7. 7.
    Parkinson D (1964) Collateral circulation of cavernous carotid artery: Anatomy. Can J Surg 7:251–268PubMedGoogle Scholar
  8. 8.
    Peterson EW, Valberg J, Whittingham DS (1969) Electrically induced thrombosis of the cavernous sinus in the treatment of carotid cavernous fistula. Excerpta Med Int Congr Series 193:105Google Scholar
  9. 9.
    Phillips B (1832) A series of experiments performed for the pupose of showing that arteries may be obliterated without ligature, compression, or the knife. Logman, London, p 66Google Scholar
  10. 10.
    Sawyer PN, Pate JW (1953) Bio-electric phenomena as an etiologic factor in intravascular thrombosis. Am J Physiol 175:103–107PubMedGoogle Scholar
  11. 11.
    Velpeau A (1831) Mémoire sur la piqure ou l’acupuncture des arte’res dans le traitement des aneurismes. Gaz Med Paris 2:1–4Google Scholar
  12. 12.
    Werner SC, Blakemore AH, King BG (1941) Aneurysms of the internal carotid artery within the skull. JAMA 116:578–582CrossRefGoogle Scholar

Copyright information

© Springer Japan 1988

Authors and Affiliations

  • Y. Hosobuchi
    • 1
  1. 1.Department of Neurological Surgery, School of MedicineUniversity of CaliforniaSan FranciscoUSA

Personalised recommendations