Tumor Spread and the Factors Influencing Prognosis in Patients with Resected Pancreatic Carcinoma

  • Parviz M. Pour
  • Yoichi Konishi
  • Günter Klöppel
  • Daniel S. Longnecker


Despite recent advances in diagnostic and therapeutic modalities for pancreatic cancer, the resectability is still low and prognosis remains poor as compared with cancer in other digestive organs [1]. In most cases, when the diagnosis is made, the tumor has extended to the outer margin of the pancreas and has infiltrated the adjacent tissues. Despite advancements in ablative surgery, the prognosis has improved little [2, 3].


Pancreatic Cancer Pancreatic Carcinoma Total Pancreatectomy Postoperative Prognosis Japan Pancreas Society 
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  1. 1.
    Jordan GL Jr (1987) Pancreatic resection for pancreatic cancer. Surgical diseases of the pancreas. In: Howard JM, Jordan GL Jr, Reber HA (eds) Surchcal diseases of the pancreas. Lee and Feibiger, Philadelphia, pp 666–714Google Scholar
  2. 2.
    Fortner JG, Kim DK, Cubilla AL, Turnbull A, Pahnke LD, Shils ME (1977) Regional pancreatectomy. en bloc pancreatic, portal vein and lymph node resection. Ann Surg 186: 42–50PubMedCrossRefGoogle Scholar
  3. 3.
    Sindelar WF (1989) Clinical experience with regional pancreatectomy for adenocarcinoma of the pancreas. Arch Surg 124: 127–132PubMedCrossRefGoogle Scholar
  4. 4.
    Pancreatic Cancer Registry of the Japan Pancreas Society (1991) Annual report of registered cases of pancreatic cancer in Japan (in Japanese).Google Scholar
  5. 5.
    Mackie CR, Dhorajiwala J, Blacstone MO, Bowie J, Moossa AR (1982) Value of new diagnostic aids in relation to the disease process in pancreatic cancer. Lancet 25: 385–389Google Scholar
  6. 6.
    Moossa AR (1989) Surgical treatment of pancreatic cancer. Cancer of the bile ducts and pancreas. In: Preece PE, Cuschieri A, Rosin RD (eds) Cancer of the bileduct and pancreas WB Saunders, Philadelphia, pp 197–208Google Scholar
  7. 7.
    Cubilla, AL, Fitzgerald P, Fortner JG (1978) Pancreatic cancer-duct cell adenocarcinoma: Survival in relation to site, size, stage, and type of therapy. J Surg Oncol 10: 465–482Google Scholar
  8. 8.
    Bottger T, Zech W, Weber W, Sorger K, Junginer T (1990) Relevant factors in the prognosis of ductal pancreatic carcinoma. Acta Chir Scand 156: 781–788PubMedGoogle Scholar
  9. 9.
    Cameron JL (1990) Carcinoma of the pancreas: Are we making progress? MMJ 39: 361–363Google Scholar
  10. 10.
    Cubilla AL, Fortner JG, Fitzgerald P (1978) Lymph node involvement in carcinoma of the head of the pancreas area. Cancer 41: 88–887CrossRefGoogle Scholar
  11. 11.
    Brooks JR, Culebras JM (1976) Cancer of the pancreas: Palliative operation, Whipple procedure, or total pancreatectomy. AmJ Surg 131: 361–520Google Scholar
  12. 12.
    Ozaki H (1992) Improvement of pancreatic cancer treatment: From the Japanese experience with the 1980s. Int J Pancreatol 12: 5–9PubMedGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1994

Authors and Affiliations

  • Parviz M. Pour
    • 1
  • Yoichi Konishi
    • 2
  • Günter Klöppel
    • 3
  • Daniel S. Longnecker
    • 4
  1. 1.The Eppley Institute for Research in Cancer; Department of Pathology and MicrobiologyUniversity of Nebraska Medical CenterOmahaUSA
  2. 2.Department of Oncological Pathology, Cancer CenterNara Medical CollegeKashihara, NaraJapan
  3. 3.Department of Pathology, Academy Hospital JetteFree University of BrusselsBrusselsBelgium
  4. 4.Department of PathologyDartmouth Medical SchoolHanoverUSA

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