Mechanism of Eosinophilia in Parasitic Infection with Special Emphasis on the Eosinophil Chemotactic Lymphokines Directed Against Different Maturation Stages of Eosinophils

  • Y. Nawa
  • M. Owhashi
  • H. Maruyama


In this review, we have demonstrated three major facets of the eosinophilic mechanism in parasitic infections. Firstly, eosinophilia is primarily a matter of cell differentiation and/or maturation from hemopoietic stem cells. During infections with tissue-invading parasites, large numbers of pluripotent hemopoietic stem cells are generated, and mobilized to extramedullary hemopoietic sites such as the liver, where they become mature eosinophils in response to the increased demand.


Parasitic Infection Schistosoma Japonicum Hemopoietic Stem Cell Mouse Bone Marrow Cell Neutrophil Chemotactic Factor 
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© Springer-Verlag Tokyo 1990

Authors and Affiliations

  • Y. Nawa
  • M. Owhashi
  • H. Maruyama

There are no affiliations available

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