Advertisement

Cardiorespiratory Adaptations of Heart Transplant Patients During a Constant Work Load Exercise at the Ventilatory Threshold

  • Alain Varray
  • Valérie Barthe
  • Jacques Mercier
  • Pierre Wintrebert
  • Bernard Albat
  • André Thévenet
  • Christian Préfaut
Conference paper

Abstract

Cardiac transplantation has become a well-accepted and successful treatment for persons with end-stage heart disease. This is due to improvements in surgical techniques and overall management (donor and organ management), but also to the rapid progress in the treatment of rejection and medical complications after transplantation. The current survival rates reported on the basis of 1200 heart transplants are 81% for 1 year and 72% for 5 years [1]. Moreover, the patients also have an enhanced quality of life due to an increased functional capacity.

Keywords

Exercise Training Cardiac Transplantation Ventilatory Threshold Incremental Exercise Test Heart Transplant Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Kriett JM, Kaye MP (1990) The registry of the international society for heart transplantation: seventh official report—1990. J Heart Transplant 9:323–330PubMedGoogle Scholar
  2. 2.
    Cerretelli P, Grassi B, Colombini A, Caru B, Marconi C (1988) Gas exchange and metabolic transients in heart transplant recipients. Resp Physiol 74:355–371CrossRefGoogle Scholar
  3. 3.
    Degre SG, Niset JM, Desmet JM, Ibrahim T, Stoupel E, et al. (1987) Cardiorespiratory response to early exercise testing after orthotopic cardiac transplantation. Am J Cardiol 60:926–928PubMedCrossRefGoogle Scholar
  4. 4.
    Kavanagh T, Yakoub MH, Mertens DJ, Kennedy J, Campbell RB, Sawyer P (1988) Cardiorespiratory response to exercise training after orthotopic cardiac transplantation. Circulation 77:162–177PubMedCrossRefGoogle Scholar
  5. 5.
    Mercier J, Ville N, Wintrebert P, Caillaud C, Varray A, Albat B, Thévenet A, Préfaut Ch (to be published) Influence of post-surgery time on transplanted heart rate in orthotopic cardiac transplant patients during exercise. Med Sci Sports ExercGoogle Scholar
  6. 6.
    Savin WM, Haskell WL, Schroeder JS, Stinson EB (1980) Cardiorespiratory responses of cardiac transplant patients to graded, symptom-limited exercise. Circulation 62:55–60PubMedGoogle Scholar
  7. 7.
    Squires RW (1991) Exercise training after cardiac transplantation. Med Sci Sports Exerc 23:686–694PubMedGoogle Scholar
  8. 8.
    Varray A, Mercier J, Terrai C, Préfaut Ch (1991) Individualized aerobic and high intensity training for asthmatic children in an exercise readaptation program: is training always helpful for better adaptation to exercise? Chest 99:579–586PubMedCrossRefGoogle Scholar
  9. 9.
    Brubaker PH, Berry MJ, Brozena SC, Morley DL, Walter JD, Paolone AM, Bove AA (1993) Relationship of lactate and ventilatory thresholds in cardiac transplant patients. Med Sci Sports Exerc 25:191–196PubMedGoogle Scholar
  10. 10.
    Mettauer B, Lampert E, Lonsdorfer J, Levy F, Geny B, Kretz JG, Carpentier A, Haberey P, Eisenmann B, Kieny R (1991) Cardiorespiratory and neurohormonal response to incremental maximal exercise in patients with denervated transplanted hearts. Transpl Proc 23:1178–1181Google Scholar
  11. 11.
    Collier CR (1956) Determination of mixed venous CO2 tension during rebreathing. J Appl Physiol 9:25–29PubMedGoogle Scholar
  12. 12.
    Jones NL (1973) Rebreathing equilibrium of CO2 during exercise. J Appl Physiol 35:538–541PubMedGoogle Scholar
  13. 13.
    Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60:2020–2027PubMedGoogle Scholar
  14. 14.
    American College of Medicine (1986) Guidelines for exercise testing and prescription, 4th edn. Lea and Febiger, PhiladelphiaGoogle Scholar
  15. 15.
    Wilkinson L (1990) Systat: The system for statistics. Systat EvanstonGoogle Scholar
  16. 16.
    Bland JM, Altman DG (1986) Statistical method for assessing agreement between two methods of clinical measurement. Lancet 8:307–310CrossRefGoogle Scholar
  17. 17.
    Kjaer M, Christensen NJ, Sonne B, Richter EA, Galbo H (1985) Effect of exercise on epinephrine turnover in trained and untrained male subjects. J Appl Physiol 59:1061–1067PubMedGoogle Scholar
  18. 18.
    Quigg RJ, Rocco MB, Gauthier DF, Creager MA, Hartley LH, Colucci WS (1989) Mechanism of the attenuated peak heart rate responsiveness after orthotopic cardiac transplantation. J Am Coll Cardiol 14:338–344PubMedCrossRefGoogle Scholar
  19. 19.
    Mercier J, Wintrebert P, Caillaud C, Varray A, Albat B, Thévenet A, Préfaut Ch (1994) Adaptations cardiorespiratoires à l’exercice du transplanté cardiaque: influence du délai post-transplantation. Science & Sports 9:1–8CrossRefGoogle Scholar
  20. 20.
    Labovitz AJ, Drimmer AM, McBride LR, Pennington DG, Wilman VL, Miller LW (1989) Exercise capacity during the first year after cardiac transplantation. Am J Cardiol 64:642–645PubMedCrossRefGoogle Scholar
  21. 21.
    Lurie KG, Bristow MR, Reitz BA (1983) Increased ß adrenergic receptor density in an experimental model of cardiac transplantation. J Thorac Cardiovasc Surg 86: 195–201PubMedGoogle Scholar
  22. 22.
    Yusuf S, Theodoropoulos S, Mathias CJ, Dhalla N, Wittes J, Mitchell A, Yacoub M (1987) Increased sensitivity of the denervated transplanted human heart to isoprenaline both before and after beta-adrenergic blockage. Circulation 75: 696–704PubMedCrossRefGoogle Scholar
  23. 23.
    Wilson RF, Christensen BV, Olivari MT, Simon A, White CW, Laxon DD (1991) Evidence for structural sympathetic reinnervation after orthotopic cardiac transplantation in humans. Circulation 83:1210–1220PubMedGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1994

Authors and Affiliations

  • Alain Varray
  • Valérie Barthe
  • Jacques Mercier
  • Pierre Wintrebert
  • Bernard Albat
  • André Thévenet
  • Christian Préfaut

There are no affiliations available

Personalised recommendations