Cellular Immune Responses to Hepatitis Viruses: Summary of a Specialty Session

  • Takao Tsuji
  • Francis V. Chisari


The cellular immune response to hepatitis virus has been considered to be a pathogenetic mechanism of hepatitis. For hepatitis A, B, and C, evidence about the involvement of cellular immunity was presented in this session. In these investigations, characterization of antigen epitopes and the close relationship between viral antigens and HLA molecules, as well as the nature of effector cells and the preferential usage of T cell repertoires were revealed. The significance of such immunological evidence in the pathogenesis of viral hepatitis was discussed.


Chronic Hepatitis Viral Hepatitis Primary Biliary Cirrhosis Cellular Immune Response Antigen Epitope 
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Copyright information

© Springer-Verlag Tokyo 1994

Authors and Affiliations

  • Takao Tsuji
    • 1
  • Francis V. Chisari
    • 2
  1. 1.First Department of Internal MedicineOkayama University Medical SchoolOkayama-shi, Okayama, 700Japan
  2. 2.The Scripps Clinic Research InstituteLa JollaUSA

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