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Histopathological Assessment in Rectal Carcinoma with Preoperative High-Dose-Rate Intraluminal Brachytherapy

  • Hidenori Yanagi
  • Masato Kusunoki
  • Youichirou Sakanoue
  • Masafumi Noda
  • Yasutsugu Shoji
  • Hiroki Ikeuchi
  • Norihiko Kamikonya
  • Yoshio Hishikawa
  • Takehira Yamamura
  • Joji Utsunomiya

Abstract

We investigated the histopathological effects of preoperative high-dose-rate intraluminal brachytherapy (HDRIBT) in 76 rectal carcinomas to know whether pathologic findings about the qualitive and quantitive assessment reflect local recurrence. The down-staging of invasion after HDRIBT was shown in 27 tumors (36.0%). There was, however, no significant difference about local recurrence rate between with and without downstaging. The proportion of residual tumor nest to stroma, which was analyzed by image analyzing system (IBAS-20, Zeis, Germany) could be better predictive factor of local recurrence than qualitive assessment in our series. When the proportion of residual tumors to stroma was less than 33%, a good local control for rectal cancer might be achieved after preoperative HDRIBT.

Keywords

Local Recurrence Rectal Cancer Local Recurrence Rate Image Analyze System Rectal Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Hidenori Yanagi
    • 1
  • Masato Kusunoki
    • 1
  • Youichirou Sakanoue
    • 1
  • Masafumi Noda
    • 1
  • Yasutsugu Shoji
    • 1
  • Hiroki Ikeuchi
    • 1
  • Norihiko Kamikonya
    • 2
  • Yoshio Hishikawa
    • 2
  • Takehira Yamamura
    • 1
  • Joji Utsunomiya
    • 1
  1. 1.Second Department of SurgeryHyogo College of MedicineNishinomiya, Hyogo, 663Japan
  2. 2.Department of RadiologyHyogo College of MedicineNishinomiya, Hyogo, 663Japan

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