Histopathological Assessment in Rectal Carcinoma with Preoperative High-Dose-Rate Intraluminal Brachytherapy
We investigated the histopathological effects of preoperative high-dose-rate intraluminal brachytherapy (HDRIBT) in 76 rectal carcinomas to know whether pathologic findings about the qualitive and quantitive assessment reflect local recurrence. The down-staging of invasion after HDRIBT was shown in 27 tumors (36.0%). There was, however, no significant difference about local recurrence rate between with and without downstaging. The proportion of residual tumor nest to stroma, which was analyzed by image analyzing system (IBAS-20, Zeis, Germany) could be better predictive factor of local recurrence than qualitive assessment in our series. When the proportion of residual tumors to stroma was less than 33%, a good local control for rectal cancer might be achieved after preoperative HDRIBT.
KeywordsLocal Recurrence Rectal Cancer Local Recurrence Rate Image Analyze System Rectal Carcinoma
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- 5.The Japanese Research Society for Colorectal Cancer (In preparation) The general rules for colorectal cancer study.Google Scholar