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Concepts and Controversies in Modelling the Coronary Circulation

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Recent Advances in Coronary Circulation

Summary

Some major concepts and controversies associated with coronary flow dynamics and the interaction between left ventricular myocardial contraction and the coronary vasculature are highlighted. The controversies rise from the interpretations of the forces acting on the intramyocardial vessels and the mechanisms postulated to affect the coronary circulation. These include the waterfall concept and the pressure-dependent resistance and compliance models which are, in essence, refinements of the intramyocardial pump concept. These are reviewed in the light of recent models of the coronary circulation. Coronary ischemia, which is typically associated with the development of collateral flow, is also presented. In addition, the important role of the collagen mesh in the generation of intramyocardial pressure (IMP) at a wide range of loading conditions and the contribution of myocardial fluid transport to IMP distribution and the coronary vasculature are included in a comprehensive model relating the interactions of the above factors.

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Author information

Authors and Affiliations

  1. Department of Biomedical Engineering, Technion-Israel Institute of Technology, Heart System Research Center, The Julius Silver Institute, 32000, Haifa, Israel

    Samuel Sideman

Authors
  1. Rafael Beyar
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  2. Dan Manor
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  3. Daniel Zinemanas
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  4. Samuel Sideman
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Editor information

Editors and Affiliations

  1. First Department of Internal Medicine, Fukushima Medical College, Hikarigaoka 1, 960-12, Fukushima, Japan

    Yukio Maruyama M.D., Ph.D. (Professor and Chairman) (Professor and Chairman)

  2. Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, 577 Matsushima, 701-01, Kurashiki, Japan

    Fumihiko Kajiya M.D., Ph.D. (Professor) (Professor)

  3. Cardiovascular Research Institute, University of California, 94143-0130, San Francisco, CA, USA

    Julien I. E. Hoffman M.D. (Professor of Pediatrics, Senior Staff Member) (Professor of Pediatrics, Senior Staff Member)

  4. University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands

    Jos A. E. Spaan Ph.D. (Professor of Department of Medical Physics, Faculty of Medicine) (Professor of Department of Medical Physics, Faculty of Medicine)

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© 1993 Springer-Verlag Tokyo

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Beyar, R., Manor, D., Zinemanas, D., Sideman, S. (1993). Concepts and Controversies in Modelling the Coronary Circulation. In: Maruyama, Y., Kajiya, F., Hoffman, J.I.E., Spaan, J.A.E. (eds) Recent Advances in Coronary Circulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68249-3_16

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  • DOI: https://doi.org/10.1007/978-4-431-68249-3_16

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68251-6

  • Online ISBN: 978-4-431-68249-3

  • eBook Packages: Springer Book Archive

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