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Effects of Coronary Collateral Circulation and Outflow Pressure Elevation on Coronary Pressure-Flow Relationships in The Beating and Non-Beating States

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Recent Advances in Coronary Circulation

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Summary

Many factors are known to influence pressure intercept and curvilinearity of coronary pressure-flow (P-F) relationships. In this paper, we focused on two of them, interarterial collateral circulation and outflow pressure elevation. We reviewed previous reports and reexamined their effects from the viewpoint of the beating/non-beating state. The presence of interarterial perfusion pressure gradients between the left anterior descending artery and the remaining vessels resulted in an increase in zero flow pressure (Pf = 0) and a more linear slope of the P-F relationship to the same degree in both the beating and non-beating states, through interarterial collateral circulation. This indicates that collateral circulation is not necessarily inhibited by cardiac contraction. Coronary outflow pressure elevation due to coronary sinus occlusion caused an increase in Pf = 0 without altering the slope of the P-F relationship, and the slope in the non-beating state shifted to the right more than in the beating state when coronary sinus pressure was elevated to the same level of 30 mmHg.

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Authors and Affiliations

  1. First Department of Internal Medicine, Fukushima Medical College, 960-12, Fukushima, Japan

    Yukio Maruyama

Authors
  1. Tomiyoshi Saito
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  2. Minoru Mitsugi
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  3. Shuichi Saitoh
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  4. Masahiko Sato
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  5. Yukio Maruyama
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Editor information

Editors and Affiliations

  1. First Department of Internal Medicine, Fukushima Medical College, Hikarigaoka 1, 960-12, Fukushima, Japan

    Yukio Maruyama M.D., Ph.D. (Professor and Chairman) (Professor and Chairman)

  2. Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, 577 Matsushima, 701-01, Kurashiki, Japan

    Fumihiko Kajiya M.D., Ph.D. (Professor) (Professor)

  3. Cardiovascular Research Institute, University of California, 94143-0130, San Francisco, CA, USA

    Julien I. E. Hoffman M.D. (Professor of Pediatrics, Senior Staff Member) (Professor of Pediatrics, Senior Staff Member)

  4. University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands

    Jos A. E. Spaan Ph.D. (Professor of Department of Medical Physics, Faculty of Medicine) (Professor of Department of Medical Physics, Faculty of Medicine)

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© 1993 Springer-Verlag Tokyo

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Saito, T., Mitsugi, M., Saitoh, S., Sato, M., Maruyama, Y. (1993). Effects of Coronary Collateral Circulation and Outflow Pressure Elevation on Coronary Pressure-Flow Relationships in The Beating and Non-Beating States. In: Maruyama, Y., Kajiya, F., Hoffman, J.I.E., Spaan, J.A.E. (eds) Recent Advances in Coronary Circulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68249-3_12

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  • DOI: https://doi.org/10.1007/978-4-431-68249-3_12

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68251-6

  • Online ISBN: 978-4-431-68249-3

  • eBook Packages: Springer Book Archive

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