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Staging of Esophageal Cancer—Preoperative Prediction of LN-Metastases

  • E. Bollschweiler
  • A. H. Hölscher
  • J. R. Siewert
Conference paper

Abstract

The therapeutic decision in esophageal cancer is decisively influenced by the preoperative staging especially the depth of wall infiltration of the primary tumor, lymph node metastases, and localization. Recent reports have clearly pointed out that radical lymphadenectomy is able to contribute to an improvement of prognosis especially in patients with early stages of lymph node metastases. In patients with an advanced stage of metastases, however, no improvement of survival can be effected by lymphadenectomy [1]. In addition, the radicality of lymphadenectomy also influences postoperative mortality and especially morbidity [2–4].

Keywords

Esophageal Cancer Preoperative Staging Radical Lymphadenectomy Preoperative Radiochemotherapy Cervical Lymph Node Dissection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Siewert JR, Bartels H, Bollschweiler E, Dittler HJ, Fink U, Hölscher AH, Roder JD (1992) Plattenepithelcarcinom des Oesophagus—Behandlungskonzepte der Chirurgischen Klinik der Technischen Universität München. Chirurg 63; 693–700PubMedGoogle Scholar
  2. 2.
    Isono K, Ochiai T, Okuyama K, Onoda S (1990) The treatment of lymph node metastasis from esophageal cancer by extensive lymphadenectomy. Jpn J Surg 20 (2): 151–7PubMedCrossRefGoogle Scholar
  3. 3.
    Kato H, Watanabe H, Tachimori Y, Iizuka T (1991) Evaluation of neck lymph node dissection for thoracic esophageal carcinoma Ann Thorac Surg. 51 (6): 931–524Google Scholar
  4. 4.
    Skinner DB (1991) Cervical lymph node dissection for thoracic esophageal cancer Ann Thorac Surg. 51 (6): 884–885Google Scholar
  5. 5.
    Bollschweiler E, Boettcher K, Hoelscher AH, Sasako M, Kinoshita T, Maruyama K, Siewert JR (1992) Preoperative assessment of lymph node metastases in patients with gastric cancer: Evaluation of Maruyama computer program. Br J Surg 79: 156–160PubMedCrossRefGoogle Scholar
  6. 6.
    Dittler HJ, Bollschweiler E, Siewert JR (1991) What is the value of endosonography in the preoperative staging of esophageal cancer? Dtsch Med Wochenschr 116 (15): 561–566PubMedCrossRefGoogle Scholar
  7. 7.
    Ziegler K, Sanft C, Zeitz M, Friedrich M, Stein H, Haring R, Riecken EO (1991) Evaluation of endosonography in TN staging of esophageal cancer GUT. 32 (1): 16–20Google Scholar
  8. 8.
    Puppe F (1990) Problemlösungsmethoden in Expertensystemen. Springer, Berlin Heidelberg, pp 200–228Google Scholar
  9. 9.
    Fletcher RH, Fletcher SW, Wagner EH (1988) Clinical epidemiology—the essentials. Williams and Wilkins, Baltimore, pp 49–57Google Scholar
  10. 10.
    Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Amer Statist Assoc 53; 457–481CrossRefGoogle Scholar
  11. 11.
    Cox DR (1972) Regression models and life tables. J Roy Statis Soc 34 (Series B): 187–220Google Scholar
  12. 12.
    Botet JS, Kightdale CJ, Zauber AG, Gerdes H, Urmacher C, Brennan MF (1991) Preoperative staging of esophageal cancer: Comparison of endoscopic US and dynamic CT. Radiology 181: 419–425PubMedGoogle Scholar
  13. 13.
    Kampschör GHM, Maruyama K, van der Velde CJH, Sasako M, Kinoshita T, Okabayashi K (1989) Computer analysis in making preoperative decisions: A rational approach to lymph node dissection in gastric cancer patients. Br J Surg 76; 905–908CrossRefGoogle Scholar
  14. 14.
    Lund O, Hasenkam JM, Aagard MT, Kimose HH (1989) Time related changes in characteristics of prognostic significance in carcinomas of the oesophagus and cardia. Br J Surg 76; 1301–1307PubMedCrossRefGoogle Scholar
  15. 15.
    Maesawa C, Tamura G, Monma N, Satodate R, Ishida K, Saito K (1991) Nuclear morphometric and DNA-content analysis of cancer cells in superficial esophageal cancer with reference to lymphynode metastases Nippon Geka Gakkai Zasshi 92 (7): 807–12Google Scholar
  16. 16.
    Nakamura T, Nekarda H, Becker K, Bollschweiler E, Hölscher AH, Siewert JR. Prognostic value of DNA ploidy and c-erb B-2 expression in adenocarcinoma of Barrett’s esophagus.Google Scholar

Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • E. Bollschweiler
  • A. H. Hölscher
  • J. R. Siewert
    • 1
  1. 1.Department of SurgeryTechnische Universität München, Klinikum rechts der IsarMünchen 80Germany

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