The Reproducibility of Ambulatory Intra-Esophageal pH Monitoring

  • S. J. Walker
  • S. Holt
  • C. J. Sanderson
  • C. J. Stoddard
Conference paper


Prolonged intra-esophageal pH monitoring is regarded as the “gold standard” test for the diagnosis of abnormal gastro-esophageal reflux, with a reported sensitivity of 88% and specificity of 98% [1]. Its use has also been advocated in patients with atypical chest pain [2], lung disease [3], and to evaluate medical and surgical treatment [4]. Although a routine investigation in many centers, the reproducibility of current ambulatory techniques has received little attention. The aim of this research project was to undertake a series of investigations in patients with suspected gastro-esophageal reflux disease and asymptomatic controls, in order to:
  1. 1.

    Determine the reproducibility of ambulatory intra-esophageal pH monitoring under standardized conditions (Study I).

  2. 2.

    Discover whether activity influences the results of pH monitoring (Study II).

  3. 3.

    Assess day-to-day variation in pH results during 5 days of continuous monitoring (Study III).



Acid Reflux Atypical Chest Pain Asymptomatic Control Subject Royal Liverpool Hospital Percentage Reflux Time 


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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • S. J. Walker
  • S. Holt
  • C. J. Sanderson
  • C. J. Stoddard
    • 1
  1. 1.University Department of SurgeryRoyal Liverpool HospitalLiverpoolUK

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